Kestine Tablets: Ebastine 10 MG 20 MG A Comprehensive Guide to Uses, Dosage, Side Effects, Price

What Is Kestine (Ebastine) Tablets Uses, Is It Good For Itching?

Kestine Tablets are mainly composed of a useful medicine named Ebastine in its formula combination. It is mainly a second-generation nonsedating antihistamine medicine. Which is normally used for the immediate relief of symptoms related to allergic diseases like allergic rhinitis and pruritus skin disease. On the other hand, it may also be used for the therapy of flu and connected symptoms too. The most crucial thing to note is that Ebastine does not show greater sedative or antimuscarinic outcomes than any other comparable medicine available in the market today in the year 2023. Kestine 10 MG Tablet Uses

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As I have told you before that this medicine belongs to the medications drug class known as antihistamines. And it contains the main generic medicine named ebastine which helps to relieve the symptoms associated with allergies like hay fever, allergic rhinitis, or hives. It works by blocking the effects of histamines which is a natural substance produced in the human body if suffering from any allergic reactions. 

Additional Product Details:
Manufacturer/Marketer Name Highnon Pharma Pvt Ltd
Manufacturer/Marketer Address 17.5 Km, Multan Road Lahore City 53700, Punjab, Pakistan
References www.ravimiregister.ee/en/Data/PIL_ENG/PIL_10430_ENG.pdf

What Is Ebastine And What Is It Used For?

The first thing we must understand is that Ebastine is a second-generation H1-Anti Histamine medication with the lowest capability to cause drowsiness in allergic patients. Moreover, the medication does not generate too much penetration to the blood-brain walls and incorporates the sufficient block of H1 Receptor in peripheral tissues causing very low incidence side effects. It was first found during studies in the year 1983 in the United States Of America. While it was first approved to use in medicines in 1990 in the USA. Now sold under several trademark names including Kestine Tablets, Ebast, Ebastel Flas, Tebast, etc

 Composition Formula Ingredients

  • 10 mg tablets contain Ebastine B.P. 10 mg.
  • 20 mg tablets contain Ebastine B.P. 20 mg.
  • Liquid Syrup 5 ml contains Ebastine B.P. 5 mg.

First You Must Understand The Allergies

First, you must understand what allergies are and how they affect our daily lives. Allergies are our body’s immune system’s response to substances it perceives as harmful, known as allergens. Common allergens include pollen, dust mites, pet dander, certain foods, and insect bites.

When our immune system encounters an allergen, it releases chemicals such as histamines that trigger allergy symptoms. These symptoms can vary from mild to severe, including sneezing, itching, watery eyes, nasal congestion, and even difficulty breathing. Allergies can significantly impact our quality of life, interfering with work, school, and daily activities.

What Are its Uses & Indications?

Kestine syrup tablets mainly provide antihistamine actions and help the patients to deliver advantages and are generally utilized for the treatment of allergy signs developed in the human body due to several sorts of various causes like

  • Allergic rhinitis associated Hay Fever ( When patients face problems like a runny nose)
  • Idiopathic chronic urticaria the nettle rashes.
  • Allergic dermatitis.
  • Sneezing Episodes
  • Skin Rashes
  • Flu & fever

Meanwhile, you must know that this medicine is not suitable for the treatment of severe allergic reactions and asthma attacks. So, in these cases, you must visit your nearby hospital or immediately talk to your doctor or pharmacist.

What Are Its Dosage Recommendations?

Kestine 20 MG Tablet Uses The Dosage of this medicine totally depends on the severity of individual patients. So do not use any quantity of dose by yourself. Always take medicine only after your doctor or pharmacist recommend it for you.

Dose In Allergic Rhinitis:

Firstly, the recommended dose is Kestine 10MG once daily. However, in the event of severe symptoms, the Dosage may increase to Kestine 20MG once daily. Furthermore, this can take in two doses of 10mg or one dose of 20 mg.

Dose In Urticaria:

However, the adult dose is 10 MG orally daily. But, doctors or pharmacists may decide according to the patient’s condition. Dosage For Allergic Dermatitis: Furthermore, The adult dose is 10 mg of orally daily.

The dosage of oral Liquid is:

Adults And Children Over 12 Years Of Age:

The recommended doses are 10MG once daily.

Children Aged 6 to 11 years:

Once doses of 5 ml kestine liquid syrup suspension once a day.

Children Aged 2 to 5 Years:

The usual doses are 2.5 ml liquid syrup once a day.

Children Under 2 Years Of Age:

Most importantly, the safety of this medication has not been established for children under 2 years of age.

Uses In Special Groups

Older Patients:

Lastly, It is not necessary to adjust the dose.

Hepatic Insufficiency:

However, It is not necessary to adjust the dose in patients with mild or moderate liver impairment. Meanwhile, there is no experience with doses over 10 mg in patients with severe hepatic insufficiency. Therefore the dose of 10 mg per day should not be exceeded in these patients.

Contra-Indications Details

Most importantly the medicine is contraindicated to Hypersensitivity to the active ingredient of the medicine.

General Warnings And Precautions

  • Most importantly, Caution should be taken when prescribing tablets in combination with azole antimycotic agents. On the other hand, type ketoconazole and itraconazole, or macrolide antibiotics type erythromycin.
  • On the other hand, Caution should be taken when the medicine is prescribed with drugs belonging to antituberculosis type rifampicin.
  • Ebastine Tab at recommended therapeutic doses does not affect the ability to drive or operate machines. However, insensitive subjects react unusually to the medicine. Therefore, It is advisable to know the individual reactions before patients drive or carry out complicated activities.
  • Meanwhile, Patients with hereditary galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption should not take this medicinal product.
  • This medicinal product may cause stomach upset and diarrhea because it contains polyethylene glycol.
  • On the other hand, the Patient with rare hereditary problems of fructose intolerance should not take this medication.

May I Use It This Tab With Other Medicines I Am Already Using?

  • Firstly, Pharmacokinetic interactions have been observed when these tablets are given with ketoconazole or itraconazole and erythromycin. Meanwhile, These Interactions resulted in increased plasma concentrations of these capsules.
  • Secondly, Pharmacokinetics interactions have been observed when the medicine is given with rifampicin. However, These interactions could result in lower plasma concentrations and reduced antihistamine effects.
  • Furthermore, No interactions have been reported between this medicine and theophylline, warfarin, cimetidine, diazepam, and alcohol.

Excipients Formula Ingredients Of Liquid Syrup

  • Glycerin
  • Lactic Acid
  • Sorbitol
  • Methyl Paraben Sodium
  • Propyl Paraben Sodium
  • Neohesperidine Dihydrochalcone
  • Polyoxin 40 Hydrogenated Castor Oil
  • Sodium Hydroxide
  • Anethole
  • Simethicone Emulsion

Excipients Formula Ingredients Of Tablet

  • Microcrystalline Cellulose
  • Lactose
  • Croscarmellose sodium
  • Pregelatinized Starch
  • Magnesium stearate
  • Hydroxypropyl Methylcellulose
  • Polyethylene Glycol (6000)
  • Titanium Dioxide (Just in 20MG Only)

Is Its Use In Pregnancy And Lactation Safe?

However, there are a limited amount of data on the use of the medicine in pregnancy. As a precautionary measure, it is preferable to avoid the use of this medication during pregnancy. Therefore, It is not known whether it is excreted in human milk. However, As a precautionary measure, it is preferable to avoid the use of this tablet during lactation.

Kestine (Ebastine) Side Effects

However, The commonly reported common and rare Side Effects are dry mouth and somnolence. Meanwhile, The other reported adverse effects are

  • Hypersensitivity Reactions
  • Nervousness
  • Insomnia
  • Headache
  • Dizziness
  • Hypoesthesia
  • Dysgeusia
  • Palpitations
  • Tachycardia
  • Abdominal pain
  • Urticaria
  • Rash
  • Dermatitis
  • Menstrual disorder
  • Edema,
  • Asthenia

Most importantly, if you face any of the described tablet side effects you may stop the medicine use and contact your doctor who will decide on the further use of the medication.

Overdosage Symptoms & Treatment Guide

Meanwhile, there is no specific antidote for this medicine. Gastric lavage, monitoring of vital functions including ECG, and symptomatic treatment are also carried out. Most importantly, you must remember to reach the nearby hospital or immediately contact your doctor in case of any medication overdose.

Meds Storage Instructions

Firstly, Keep out of the reach of children. Most importantly, Store below 30 C in a dry place. On the other hand, Protect from sunlight and heat. Lastly, you must read the product pack for its expiry date. And if the product is known as expired you must not use it.

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Kestine (Ebastine) 10MG, 20MG Tablets Capsules Price Details

  • Price In Pakistan: 296 PKR
  • Price In USA: $ 5 USD (Without Insurance Cost)
  • Price In India: 185 INR

FAQ (Peoples Frequently Asked Questions) About Kestine Tab

  • Q No.1: What Are Kestine Tablets?

Mainly it is a medication which normally indicated for the treatment of allergic conditions like seasonal allergies, hives, and rhinitis.

  • Q No.2: How Does This Medicine Work?

It works by blocking the action of a human body’s natural chemical named histamine which produce by the body during any type of allergic disease. Therefore it provides immediate relief against these symptoms in a short time only.

Q. No. 3: Can Children Take This Medicine?

The most important thing is that this medicine is not recommended to use by patients who aged below 12 years of age like children.

  • Q.No.4: Can Kestine Tab Cause Any Type Of Drowsiness?

In only some rare cases it can cause drowsiness. So it’s important to avoid driving or operating any type of heavy machinery until you know how this medicine can affect one.

Disclaimer

All the information about product uses, dosage side effects, formula, ingredients, indications, contraindications, drug interactions, warnings & precautions as well as it’s safe to use during pregnancy and lactation is purely based on the information available on the internet. And it is only provided here for general education and information purposes only. So do not take action about any of the information you found here because we do not guarantee the authenticity of each and every piece of information available on this website. All the information we produced is purely based on FDA-approved literature and does not substitute professional medical advice. This information is not intended to substitute medical advice, diagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical condition.

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