Gabica Tablets

One of the best medicine Gabica Brand Name is Tablets/Capsules. It is the first drug approved by FDA for the treatment of fibromyalgia. Lyrica is also used for the relief of nerve pain or seizures. While the main ingredient of the medicine Tablets/Capsules is chemically similar to the drug Neurontin (Gabapentin). Most importantly it is manufactured and marketed world wde by Getz Pharma Intl.

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Gabica Tablets Drug Composition

• Gabica Capsules 50 MG Contains : Pregablen 50 MG
• 75 MG Gabica Capsules Contains : Pregablen 75 MG
• Gabica 100 MG Capsules Contains : Pregablen 100 MG
• Gabica 150 MG Capsules Contains : Pregablen 150 MG
• 300 MG Gabica Capsules Contains : Pregablen 300 MG

Gabica Tablets Special Populations

Renal Impairment

Meanwhile, Pregablen plasma clearance and renal clearance are directly proportional to creatinine clearance. Pregablen clearance reduced in patients with impaired renal function. While Tablet Medicine Dosage adjustments required in patients with renal impairment. The Tablets effectively removed by hemodialysis (following 4 hours hemodialysis treatment plasma Pregablen concentrations reduced by approximately 50). The dose of Gabica Drug adjustments required for patients on hemodialysis.

Older Patients (Over 65 years of age)

Tablets Capsules’ clearance tends to decrease with increasing age. This decrease in Pregablen oral clearance consistent with decreases in creatinine clearance associated with increasing age. Reduction of Dose may require in patients who have age-related compromised renal function.

Gabica Medicine Uses & Indications

• The Tablets Capsules Uses for the management of neuropathic pain associated with diabetic peripheral neuropathy.
• Tablets Medication Uses For the management of postherpetic neuralgia.
• Medicine Uses For the treatment of pain associated with spinal cord injury.
• As adjunctive therapy in adults with partial seizures with or without secondary generalization.
• Medicine Used For the treatment of Generalized Anxiety Disorder (GAD) in adults.
• For the treatment of fibromyalgia syndrome.

Gabica Tablets Dosage

Capsules Dosage used orally with or without food. When discontinuing Gabica taper gradually over a minimum of 1 week irrespective of the indication.

Neuropathic Pain Associated With Diabetic Peripheral Neuropathy

Capsules treatment can be started at a dose of 150 MG per day given as 2-3 divided doses. Based on individual patients’ response and tolerability. The dosage may be increased to 300 MG per day given as 2 divided doses. After an interval of 3 to 7 days and if needed to a maximum dose of Gabica Tablets 600 mg per day after an additional 7 days interval.

Postherpetic Neuralgia

The recommended dose of Gabica 75 mg to 150 mg two times a day or 50 mg to 100 mg three times a day (150 mg to 300 mg day). Dosing should begin at 75 mg two times a day or 50 mg three times a day (150 mg /day ). And maybe increased to 300 mg/ day within 1 week based on efficacy and tolerability. Patients who do not experience sufficient pain relief following 2 to 4 weeks of treatment with 300 mg/day. And who are able to tolerate may treat up to 300 mg two times a day (600mg/day).

Neuropathic Pain Associated With Spinal Cord Injury

The recommended starting Gabica dose is 75 mg times a day (150mg/ day). The dose may be increased to 150 mg two times a day (300 mg/day) within 1 week based on efficacy and tolerability. Patients who do not experience pain relief following 2 to 4 weeks of treatment with 300 mg two times a day (600mg/ day).

Adjunctive Therapy In Adults With Partial seizure With Or Secondary Generalization

tablets treatment can started with a dose of 150 mg per day given as 2-3 divided doses. Based on individual patients’ response and tolerability the dosage may increased to 300 mg per day after 1 week. does not alter the plasma concentrations of other commonly used anticonvulsant drugs. Similarly, commonly used anticonvulsant drugs do not alter plasma concentrations of Pregablen.

General Anxiety Disorder

dose for Anxiety is 150 mg to 600 mg/day given as two or three divided doses. The need for treatment should reassessed regularly. Pregablen treatment can be started with a dose of 150 mg/ day given as 2-3 divided doses. Based on individual patients’ response and tolerability the dosage may be increased to 300 mg /day after 1 week. Following an additional week, the dosage may be increased to 450 mg/ day. The maximum dosage of 600 mg/day may be achieved after an additional week.

Fibromyalgia Syndrome

The recommended dose of Pregablen for fibromyalgia is 300 mg to 450 mg/day. Dosing should begin at 75 mg two times a day or 50 mg three times a day (150 mg/day). And maybe 300 mg/day within 1 week based on efficacy and tolerability. Patients who do not experience sufficient benefit with 300 mg /day may further increased to 225 mg two times a day (450mg/ day).

Medicine Gabica Side Effects

Very Common Drug Side Effects

• Dizziness Drowsiness Somnolence

Gabica Medication Common Side Effects

• Increased Appetite Euphoric Mood Confusion Irritability Decreased Libido
• Abnormal coordination Tremor Ataxiadysarthria Memory Impairment
• Balance Disorder Headache Blurred Vision Diplopia
• Dry Mouth Constipation Flatulence Erectile Dysfunction
• Feeling Drunk Peripheral Oedema Insomnia Sedation
• Fatigue Weight Increase Disorientation Paraesthesia
• Vertigo Gait Abnormal Vomiting

Tablets Uncommon Side Effects

• Nasopharyngitis Anorexia Hypoglycemia Hallucination
• Panic Attack Restlessness Agitation, Depression
• Depressed Mood Mood Swings Depersonalisation Word Finding Difficulty
• Nystagmus Speech Disorder Cognitive Disorder Stupor
• Myoclonus Ageusia Dyskinesia Syncope
• Dizziness Postural Intention Tremor Hyporefilexia Hypoaesthesia
• Amnesia Hyperaesthesia Burning Sensation Visual Disturbance
• Eye swelling Visual Filed Defect Eye Asthenopia Visual acuity reduced
• Dry Eye Hyperacusis Tachycardia Lacirmation Increased
• Flushing Hot Flushes Hypotension Apathy
• Dyspnoea Nasal Dryness Rash Papular Abdominal distension
• Salivary Hypersecretion Hypoaestheasia Oral Hyperhiddrosis Anorgasmia
• Muscle Twitching Joint Swelling Muscle Cramp
• Myalgia Arthralgia Back Pain Pain in Limb
• Muscle stiffiness Urinary Incontinence Chest Tightness Asthenia
• Thirst Pain Feeling Abnormal Platelet Count Decrease
• Aspartate Aminotransferase Increased and Platelet Count Decreased
• Dysuria Ejaculation Delayed Sexual Dysfinction Fall
• Abnormal Dreams libido increased
• Psychomotor Hyperactivity
• Atriroventricular block first degree
• Gastrooesophageal reflux disease
• Blood Creatine Phoshokinase Increased
• Alanine Aminotransferase Increased

Gabica Tablets Rare Side Effects

• Neutropenia Disinhibition Elevated Mood Hypokinesia
• Parosmia Dysgraphia Peripheral Vision Loss Oscillopsia
• Eye Irritation Mydriasis Strabismus Visual brightness
• Sinus Tachycardia Sinus Bradycardia Sinus Arrhythmia Perip- Coldness
• Epistaxis Pancreatitis Dysphagia Urticaria
• Cold Sweat Rhabdomyolysis Cervical Spams Neck Pain
• Renal Failure Oilguria Amenorrhoea Breast Discharge
• Breast Pain Dysmenorrhoea Breast Enlargement Gynaecomastia
• Generalised Oedema Pyrexia Blood Glucose Increase Weight Decrease
• White Blood Cell Decrease Blood Creatinine Increased
• Altered Visual Depth Perception Photopsia Blood Potassium Decreased

Gabica Tablets Contraindications

Tablets Capsules contraindicated in patients with a known hypersensitivity to Pregablen or any of the components of the Drug. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.

Gabica Capsules Precautions

Withdrawal of Antiepileptic Drugs (AEDs)

As with all AEDs, Pregablen Capsules should withdraw gradually to minimize the potential of increased seizure frequency in patients with seizure disorders. On the other hand, If Tablets is discontinued this should be done gradually over a minimum of 1 week.

Angioedema

Drug should be discontinued immediately if symptoms of angioedema, such as facial, perioral or upper airway swelling occur.

Weight Gain

Capsules associated with weight gain related to dose and duration of exposure. Meanwhile, Some diabetic patients who on Pregablen treatment may need to adjust hypoglycemic medications.

Discontinuation

After discontinuation of short term and long term treatment with Pregablen withdrawal symptoms have observed in some patients. Meanwhile, The following events have mentioned

• Insomnia Headache Nausea Diarrhea
• Flu Syndrome Nervousness Depression Pain
• Sweating Dizziness.

Creatinine Kinase Elevation

medicine should be discontinued if myopathy diagnosed or suspected or if markedly elevated creatine kinase levels occur.

Congestive Heart Failure

There have been reports of congestive heart failure in some patients receiving Medicine. These reactions mostly seen in old patients cardiovascular compromised patients during Pregablen treatment for a neuropathic indication. Therefore, Pregablen should use with caution in these patients. Discontinuation of Medicine may resolve the reaction.

Alcohol

Most importantly, Patients should told to avoid consuming alcohol white on Pregablen. Because it may potentiate the impairment of motor skills and sedation of alcohol.

Effects on Ability to Drive and Use Machines and Injuries

Meanwhile, Tablets may cause dizziness and somnolence. Therefore may have an influence on the ability to drive or use machines. Or may increase the occurrence of accidental injuries especially in the population.

Pediatrics

Medicine is not recommended for use in children below the age of 12 years and adolescents (12-17 years ) due to insufficient data on safety and efficacy. Meanwhile, consult your doctor and pharmacist he will decide according to the condition of the patients.

Pregnancy

However, there are no adequate and well-controlled studies in pregnant women. Drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Nursing Mothers

However, It is not known whether Tablets is excreted into human milk. Because many drugs are excreted in human milk, caution should be exercised when Medicine administered to a nursing woman. Therefore, always contact your doctor or pharmacist if you are pregnant and starting the medicine.

Gabica Interactions

However, patients who require concomitant treatment with CNS depressants such as opiates or benzodiazepines. They should informed that they may experience additive CNS side effects somnolence. On the other hand, Pregablen may potentiate the effects of ethanol and lorazepam. Therefore also some reports of respiratory failure and coma in patients taking Pregablen and other CNS depressant medications. On the other hand, Medicine Tablets appears to be additive in the impairment of cognitive and gross motor function caused by oxycodone.

Medicine Overdose

The most common Side Effects observed in Pregablen Overdosage symptoms includes Like

• Somnolence
• Confusional State
• Agitation And Restlessness
• Cases of coma have also reported.

Meanwhile, Treatment of Overdosage should include general supportive measures and may include hemodialysis if necessary.

Gabica Drug Storage Instructions

Firstly, Store the drug between 15C to 30C temperature. On the other hand, protect the tablets from sunlight and heat. Secondly, also keep safe from moisture. Most importantly, always store your medicine out of the reach of your small children. Lastly, and most importantly you must read all the packing of the Gabica product for its expiry date. If the medicine expired you must not use the medicine to avoid all kind of harmful effects to your life.

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Gabica 50 MG, 75 MG, 100 MG, 150 MG, 300 MG Tablets/Capsules