A Brief Guide Of Gravibinan Injection Progesterone IVF Uses Side Effects Price

What Are Gravibinan (Progesterone) Injections Uses Dosage Side Effects?

Gravibinan Injection contains Estradiol and Progesterone in it. Progesterone Injection is an important hormone which also called as pregnancy hormone. it mainly acts on the uterus in sequence with estrogen, to prepare the endometrium to receive the fertilized ovum. It is used for the treatment of abnormal uterine bleeding, and many types of cancers, used for contraception, and to treat amenorrhea. While Estradiol is a naturally occurring hormone used along with this medication for contraception, menstrual disorders, and the suppression of certain cancers, and also for the prevention of osteoporosis. Most importantly Bayer Pharma Pvt Ltd is the manufacturer and marketer of this product all over the world.

More Links:  Vastarel MR 35 MG Tablets Uses, Dosage, Side Effects Benefits Formula Ingredients Price

Composition Ingredients & Formula

1 ML Injection contains <———->  250 mg Hydroxy Progesterone Caproate and 5 mg estradiol valerate in an oily solution.

Gravibinan Injection Uses & Indications

These Progesterone Injections IVF use and indicated in Prophylaxis threatened to start developing a baby in the early stages. However, the expert physician and doctor may use it for several other disorders.

Gravibinan Injection Dosage And Method Of Administration

Like all oily solutions Gravibinan must be injected intramuscularly. Experience shows that short-lasting reactions like:

• Urge to cough
• Coughing fits
• Respiratory distress

which occur in rare cases during or immediately after the use of the Injection of oily solutions can be avoided by injecting the solution extremely slowly.

• Prophylaxis

There days after the risk in basal body temperature on about the 18th day of the cycle, 1ml is injected intramuscularly. When conception has not occurred, the basal body temperature falls again in the premenstrual period. And there will be normal or, occasionally, rather heavier menstrual bleeding. Sometimes the fall in temperature may be delayed for 2-3 days. Where failure of the menstrual bleeding and continued elevation of the basal body temperature indicate early pregnancy.

An intramuscular injection of this medication is given immediately. The hormone dose doubled one week later i.e. from the beginning of the sixth week of pregnancy on (the pregnancy is reckoned as starting on the first day of the last menstruation): 2ML is administered intramuscularly every week during the first months of pregnancy, in isolated cases even longer. The diagnosis of pregnancy should be confirmed by an immunological pregnancy test about two weeks after the failure of the expected menstruation.

Therapy is also advantageous when a patient with a predisposition to habit does not come for treatment until after the start of the fresh pregnancy. Progesterone Injection 2ML IVF is injected intramuscularly immediately. Followed by 2 ml intramuscularly every week during the first months of pregnancy. In isolated cases, it is used even longer.

• Threatened

To institute treatment 2 ml is injected intramuscularly twice weekly until the bleeding stops. Bed rest is urgently advised during this time. When the bleeding ceases. 2 ml Gravibinan gave intramuscularly weekly for some weeks until the patient remains free from complaints and bleeding despite mobilization. Whether this medication therapy is to be continued as a prophylactical measure must be decided individually.

Injection Contraindications Details

Firstly, the Injections are contraindicated in a history of herpes during pregnancy and thromboembolic processes.

Special Warnings And Precautions

According to the present state of scientific knowledge, medicinal therapy should be given in early pregnancy only if it is absolutely essential. This is also valid for the use of hormone preparations such as medication for the maintenance of pregnancy. Consequently, this medication should only be prescribed if there is an urgent desire for children-primarily in the presence of corpusluteum insufficiency or a case history Because it places the uterus at rest, it is possible for an already dead embryo to be retained.

In the case of protracted therapy, it is, therefore, necessary to check the continued existence of pregnancy by means of appropriate examinations and immunological tests. It has been concluded from epidemiological surveys that the use of oral estrogen/progestogen-containing ovulation inhibitors is attended by an increased incidence of thromboembolic diseases. Although no such associations are suspected for injectable steroidal preparations of similar composition. One should keep the possibility of an increased thromboembolic risk in mind. Particularly where there is a history of thromboembolic changes or sickle-cell anemia.

Gravibinan Progesterone Injection Possible Teratogenic Side Effects

Like all the other medicines Gravibinan Progesterone Injections IVF minor Side Effects in some patients. A possible association between the administration of female hormones in early pregnancy and the occurrence of malformations has the present state of scientific knowledge. The assumption that there may be a causal association can regard as unfounded. However, it must be clearly understood, that no drug- including these hormones-can claimed with absolute certainty to be free from teratogenic effects.

Drug Interactions Information

The requirement for oral anti-diabetics or insulin can change.

Gravibinan Progesterone Injection IVF Use During Pregnancy And Lactation

In view of the therapeutic indications, a reference to the Injection IVF use during pregnancy and lactation is irrelevant. So most importantly, you must consult your doctor or physician if you planned to get pregnant. Or already have a pregnancy before using these injections.

Gravibinan Progesterone IVF Injection Side Effects

Strict medical supervision is necessary if the patient suffers from diabetes. 8 to 14 days after unsuccessful treatment of threatened and subsequent curettage withdrawal bleeding may occur in isolated cases. Owing to the continuing Side Effects which subside only gradually. However, no further measures are necessary.

Overdose Symptoms & Treatment

Acute toxicity studies showed that medicine is to be classified as practically non-toxic. No risk of toxicity is to be expected even after an inadvertent single administration of a multiple of the dose required for therapy.

Pharmacological Properties

• Pharmacodynamic Properties

The prophylactic use of the inj in habitual or uterine hypoplasia improves nidation conditions for a fertilized ovum by making good the deficit of hormones. Growth of the uterus is stimulated and a state of quiescence is subsequently induced. The therapy of threatened injection has the effect of placing the uterus in a state of quiescence. The hormone combination also increases the metabolic capacity of the placenta. Thus promoting further development of the conceptus.

Inj Gravibian Storage Instructions

Store the injection below 30 C temperature. Protect from heat and sunlight. Always keep all the medicine out of the reach of the children. Most importantly always check the injection pack before you use it to look for its expiry date printed on each pack. And if it expired do not use it as it may create some serious life threats for the patients.

• Conclusion:-

Gravibinan IV Injection represents a groundbreaking advancement in the treatment of low Progesterone. With its unique mechanism of action, minimal side effects, and long-term benefits, it offers a comprehensive solution for patients seeking relief from Progesterone deficiency symptoms. Always discuss with your healthcare provider, physician, or doctor before you start using this inj to avoid any type of harmful side effects or threats to your health.

The most important thing to remember is that your health and your life are more important and totally rely on choosing the right treatment which can make all the difference in your quality and healthy life. With Gravibinan Injection, a brighter and healthier future awaits those suffering from Progesterone deficiency.

More Medical Information:

Gravibian Progesterone IVF Injection Price

• Price In Pakistan= 532 PKR

References:-

• https://dawaai.pk/medicine/gravibinan-1-37343.html
• https://oladoc.com/pharmacy/medicine/gravibinan-injection-2ml
• https://www.dvago.pk/p/gravibinan-injection-1-ampx2-ml
• https://nexthealth.pk/product/gravibinan-inj-1ampx2ml-2527/