Lorin NSA Tablet Syrup Loratadine 10 MG Uses Dosage Side Effects Benefits Price

Lorin NSA Syrup Tablets Uses Dosage For Child & Adults

Lorin NSA Tablet Syrup contains Loratadine in it. Loratadine is an oral no sedating H-1-blocker. It is almost similar in structure to cyproheptadine and azatadine. Meanwhile it differs structurally from the other non-sedating H-blockers terfenadine and astemizole. Mostly loratadine used in combination with pseudoephedrine and decongestant medications. Most importantly, it used to relief the symptoms associated with seasons allergic rhinitis like hay fever and hives. It first discovered in studies in year 1980 and first approved to use in medicine in USA in year 1988.

 

Lorin Tablets Syrup Composition, Ingredients & Formula

• Each 10 mg tablet contains  :    Loratadine 10 MG
• Each 5 ML syrup contains      :     Loratadine 5 MG

Loratadine Lorin NSA Tablets Syrup Uses For Child And Adults

Lorin NSA (Loratadine) Tablet Syrup used and indicated for the relief of nasal and non-nasal symptoms of seasonal allergic rhinitis. Meanwhile it also use for the treatment of chronic idiopathic urticaria in patients 2 years of age or older.

Uses In Urdu Hindi

Lorin NSA Loratadine Syrup Tablets Dosage And Administration

Lorin NSA Dosage For Adults And Children 6 Years Of Age And Over: The recommended (Lorin NSA) Dose is one 10 mg tablet or 2 teaspoonfuls (10 mg) syrup once daily. However, only your doctor or pharmacist will decide the exact dosage of syrup or tablet according child or adult symptoms. Dose Of Lorin NSA For Children 2 To 5 Years Of Age And Over; The recommended (Lorin-NSA) Syrup Dosage is 5 5 mg (1 teaspoonful) once daily. In Adults And Children 6 Years Of Age And Over with Liver Failure Or Renal Insufficiency (GFR< 30 mL/min): The  starting dose of this product should be 10 mg (one tablet or two teaspoonfuls) every other day. On the other hand, use lorin nsa In children 2 to 5 years of age with liver failure or renal insufficiency, the starting dosage should be 5 mg (one teaspoonful) every day.

Lorin NSA (Loratadine) Tablets Syrup Special Populations

Pediatric:

the pharmacokinetic profile of this medication in babies in the 2 to 12 years age age group is similar to that of adults.

Geriatric:

The mean elimination half-lives for the geriatric subjects were 18.2 hours for the medicine and 17.5 hours for descarboethoxylorateadine.

Renal Impairment:

The mean elimination half-lives of this medication (7.6 hours) and descarboethoxyloratadine (23.9 hours) were not substantially different from that observed in normal subjects. Hemodialysis Does not have an effect on the pharmacokinetics of this medication or descarbothoethoxyloratadine in subjects with chronic renal impairment.

Hepatic Impairment:

The elimination half-lives for loratadine and descarboethoxyloratadine were 24 hours and 37 hours, respectively, and increased with increasing severity of liver disease.

Lorin NSA (Loratadine) Syrup Tablets Side Effects

The most commonly reported Loratadine side-effects are

• Fatigue
• Dry mouth
• Allergic symptoms like rash
• Headache
• Gastrointestinal disturbances (e.g. gastric upsets/nausea)

Meanwhile, the more uncommon side-effects include alopecia, anaphylaxis and an abnormal hepatic functioning. On the other hand, less frequent incidences of abnormal hepatic function including hepatitis, jaundice and hepatic necrosis have reported.

Drug Interactions

Most importantly, when administered concomitantly with alcohal, with this medicine has no potentiating effects as measured by psychomotor studies. However, Increase in plasma concentrations of this product have reported after concomitant use with ketoconzole, erythromycin or cimetidine in controlled clinical trials. But only without clinically significant changes (including electrocardiographic). Meanwhile, other drugs known to inhibit hepatic metabolism should be co administered with caution until definitive interaction studies can completed.

Drug/Laboratory Test Interactions:

It should discontinued approximately prior to skin testing procedures since antihistamines may prevent or diminish otherwise positive reactions to dermal reactivity indications.

Lorin NSA Tablets Syrup Uses Precautions For Child & Adults

General Precautions:

• Patients with liver impairment or renal insufficiency (GFR< 30 ml/min) should be given a lower initial dose (10 mg every other day).
• The medication lacks significant may effects. Patients should however be warned that a small number of individuals may experience sedation. Patients experiencing sedation or impaired concentration should be advised not be drive or  perform complicated tasks.  Sedation may be enhanced by the simultaneous intake of alcohol of other complicated system depressants.

Pregnancy Category B:

However, there was no evidence of animal teratogenicity. There are, however, no adequate and well-controlled studies in pregnant women. because animal reproduction studies are not always predictive of human response, It should be used during pregnancy only if clearly needed.

Nursing Mothers:

This medicine and its metabolite, descarbothoxy loratadine, pass easily into breast milk. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Caution should be exercised when it is administered to a nursing women.

Pediatric Use:

Meanwhile, the safety of syp at a daily dose of 10 mg demonstrated in 188 pediatric patients  6 to 12 years of age. On the other hand, the safety and tolerability of syrup at a daily dose of 5 mg has demonstrated in 60 pediatric patients 2 to 5 years of age. However, the safety and effectiveness of this medicine in children under 2 years of age have yet established.

Lorin-NSA Overdosage Symptoms And Treatment

However, In adults, somnolence, tachycardia, and headache have reported with overdoses greater than 10 mg with the tablet formulation (40 mg -180 mg). Meanwhile, Extrapyramidal signs and palpitations reported in children with overdose of greater than 10 mg of the syrup. Most importantly, In the event overdoses general symptomatic and supportive measures should instituted promptly and maintained for as long as necessary. Treatment of overdosage would reasonably consist of emesis (ipecac syrup), expect in patients with impaired consciousness, followed by the administration of activated charcoal to absorb any remaining drug. If vomiting unsuccessful, or contraindicated, gastric lavage should performed with normal saline. Saline cathartics may also of value for rapid dilution of bowel contents. On the other hand, the medicine not eliminated by hemodialysis. Meanwhile, It not known if it eliminated by peritoneal dialysis.

 Contraindications

Patients with known hypersensitivity to this medication or any of the ingredients of Loren-NSA Tab Syp.

 Storage Instructions

Most importantly, always remember to keep all your medicine out of the reach of your kids at home. On the other hand, protect Lorin-NSA Tab Syp from direct sunlight and heat. Meanwhile, also store the tablets and syp below 30 C room temperature.

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Lorin NSA (Loratadine) Tablets Syrup Price Details

• Price In Pakistan= 188 PKR
• Price In India= 167 INR
• Price In USA= 3 USD

 

Disclaimer

All the details of the medicine provided on this website Pharmacy Online Here are only for informational purposes and there is no intent to substitute for professional medical advice, diagnostic, and treatment purposes. Therefore, always get medical advice from any qualified healthcare provider doctor, or pharmacist for any questions about your medical conditions, symptoms, or disorder. So do not disregard the medical advice of your professional healthcare provider or delay it simply because of the information your read here on this website.  Note:– Always Use Any Type Of Medicines Only Under The Supervision Of A Professional Healthcare Provider, Doctor, Or Pharmacist.