Doxofylline Tablets Ofylin 400 MG Uses, Dosage, Side Effects, Benefits Full Medicine Information
Ofylin Tablets 400 MG
Doxofylline brand name is Ofylin Tablets 400 MG. Doxofylline Tablets is a new Generation Xanthine medicine which belonging to a new class of drug referred to as (Novofylline). Which is chemically 1,3- Dimethyl 3,7 dihydro purine 2,6 dione. Its molecular is C11H14O4 and the molecular weight is 266.3. So, here is all the necessary and essential Drug Information about Ofylin 400 MG (Doxofylline) Tablets.
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Ofylin Tablets 400 MG Composition
OFYLIN 400 MG Tablets : Each tablet contains Doxofylline 400 MG
Doxofylline Ofylin Tablets Indications
Mostly, Ofylin (Dosofylline) Tablets is used for the treatment of symptoms like
- Bronchial Asthma
- Chronic Obstructive Pulmonary Disease (COPD)
Doxofylline Dosage Administration
Doxofylline (Ofylin 400 MG) Tablet Dosage : Elderly patients 1/2 tablet two or three times daily.
Ofylin (Doxofylline 400 MG) Tablets Dosage : Adults 1 tablet two or three times daily
Ofylin 400 MG Tablets Contraindications
Firstly, this Drug Contraindicate in individuals who have shown hypersensitivity to its components. Furthermore, it also contraindicated in patients with acute:
- Myocardial Infarction
- Hypotension
- Lactating women
Doxofylline (Ofylin) Drug Overdose
Although on major arrhythmias have been documented with Doxofylline. However, the occurrence of major cardiac rhythm disturbances cannot be excluded in cases of overdosage of xanthine compounds. Meanwhile, If a potential drug oral overdose is established the patient may present seizures. Moreover, these symptoms could be the first sign of intoxication. Therefore, adverse reactions may cause withdrawal from treatment. On the other hand, there is no specific antidote. However, It suggested that the management principles should institute according to the relief of a symptom of cardio-circulatory shock.
Doxofylline (Ofylin) Use In Special Population
Doxofylline In Pregnancy And Lactation
Meanwhile, Animal reproduction studies indicate that Doxofylline Dose does not cause fetal harm. When administered to pregnancy nor can affect reproduction capacity. However, since there is limited experience in humans during pregnancy. On the other hand, Xanthiness should be given to pregnant women only if clearly needed.
Ofylin 400 MG In Lactation
Furthermore, Ofylin Tablets contraindicated in nursing mothers.
Doxofylline Tablets Warnings
Most importantly, Use Doxofylline Tablets with caution in patients with like
- Hypertension
- Heart Disease
- Hypoxenmia
- Hyperthyroidism
- Chronic
- Right Ventricular Failure
- Congestive Heart Failure
- Liver Disease
- Renal Disease
- With History of Peptic Ulcer
- In the elderly
- Frequently
- Patients with congestive heart failure have markedly prolonged drug plasma levels following discontinuation of the drug.
Doxofylline 400 MG Drug Precautions
The half-life of Xanthine derivatives is influenced by a number of known variables. Therefore, It may be prolonged in patients with liver disease, in patients with congestive heart failure. However, In those affected with chronic obstructive lung disease or concomitant infections. And in those patients taking certain other drugs Like
- Erythromycin
- Troleandromycin
- Lincomycin
- Anti flu vaccine
Therefore, In these cases, lower Doxofylline Tablets Dosage may need. Phenytoin other anticonvulsants and smoking may cause an increase in clearance with shorter mean half-life. In these cases, higher doses of Doxofylline may be needed. On the other hand, Laboratory monitoring of plasma concentration of Doxofylline recommended in all the above situations.
Ofylin 400 MG Drug Interactions
Doxofylline (Ofylin) Tablets should not be administered together with other Xanthine derivatives. Meanwhile, Toxic synergism with ephedrine has documented for xanthine. Like other xanthines concomitant therapy with erythromycin. lincomycin, clindamycin, allopurinol, cimetidine, propranolol. And anti-flu vaccine may decrease the hepatic clearance of xanthines causing an increase in blood levels. Meanwhile, No evidence of a relationship between Doxofylline serum concentrations and toxic events has been reported.
Doxofylline Side Effects
After Doxofylline (Ofylin) Tablets administration occasionally Side Effects like:
- Nausea
- Vomiting
- Cephalagia (headache)
- Irritability
- Insomia
- Palpitations
- Tachycardia may occur.
Meanwhile, If a potential oral overdose established, the patients may present with severe arrhythmias and seizures. These symptoms could the first sign of intoxication. On the other hand, Doxofylline 400 MG Tablets Side Effects may cause withdrawal from treatment. Meanwhile, a lower dose re-challenge may start only after the advice of a physician.
Ofylin 400 MG Tablets Drug Storage Instructions
Firstly, Store the drug below 30 C temperature. On the other hand, Protect from sunlight and heat exposure. In addition, Store the medicine in a dry place. Most importantly always keep your medicines out of reach of your kids. Furthermore, you must read the packing for the product expiry date.
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Ofylin (Dosofylline) 400 MG Tablets

