Feldene (Piroxicam) Gel

Feldene Gel 25 G Cream contains a very useful which also considered as the best medicine to treat the pain inflammation named Piroxicam. Piroxicam is a nonsteroid inflammatory agent used in the treatment of inflammatory conditions. Although the mode of action for this drug agent is not precisely understood. Meanwhile, Piroxicam inhibits prostaglandin synthesis and release through reversible inhibition of the cyclooxygenase enzymes.

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Feldene Cream Composition

The Gel contains 0.5% (5 mg per gram of gel) by eight anhydrous piroxicam.

Feldene Gel Uses

Firstly, Feldene Gel normally indicated and use for a variety of conditions characterized by pain and inflammation such as

• Osteoarthritis
• Arthrosis
• Degenerative joint disease
• Posttraumatic Musculoskeletal Disorders
• Acute musculoskeletal disorders
• Tendinitis
• Tenosynovitis
• Periarthritis
• Sprains
• Strains
• Low back pain

Posology And Method Of Administration

This Piroxicam Cream is intended for external use only. Meanwhile, A 1 gram dose of the 0.5% gel (corresponding to 5 mg of piroxicam should apply to the affected site three or four times per day. In addition, No occlusive dressing should be employed. On the other hand, Rub in the gel, leaving no residual material on the skin.

Use In Children

Dosage recommendations and indications for use in children have been established.

Feldene Cream Contraindications

• Piroxicam Gel topical should not be used in those patients who have previously shown hypersensitivity to the gel or cream or piroxicam in any of its dosage forms.
• The potential exists for cross-sensitivity to aspirin and other non_ steroidal anti _ inflammatory drugs (NSAIDs)
• Piroxicam topical not given to patients in whom aspirin and other NSAID induce the symptoms of asthma, rhinitis, angioedema or urticaria.

Feldene Cream Gel Special Warnings And Precautions For Use

Life-threatening cutaneous reactions, Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) have been reported with the use of systemic administration of piroxicam. These reactions have not associated with topical piroxicam, but the possibility of occurring with topical piroxicam cannot ruled out.

Patients should advised of the signs and symptoms and monitored closely for skin reactions. The highest risk for occurrence of SJS or TEN within the first week of treatment. If signs or symptoms of SJS or TEN (e.g. progressive skin rash often with blisters or mucosal lesions) presented should discontinued.

The best results in managing SJS and TEN come from early diagnosis and immediate discontinuation of any suspect drug. Early withdrawal associated with a better prognosis. If the patient has developed SJS or Ten with the use of piroxicam, piroxicam must not restart in this patient at any time. If local irritation develops, the use of piroxicam topical discontinued and appropriate therapy instituted as necessary. Do not apply to the eyes, mucosa, or open skin lesions, or skin conditions affecting the site of application.

NSAIDs, including piroxicam, may cause interstitial nephritis, nephrotic syndrome, and renal failure. There have also been reports of interstitial nephritis, nephrotic syndrome, and renal failure with topical piroxicam, although the causal relationship to treatment with topical piroxicam has not been established. As a result, the possibility that these events may be related to us of topical piroxicam cannot be ruled out.

Feldene Gel Drug Interactions

Based on the mechanism of action, the use of NSAIDs, including piroxicam may delay or prevent the rupture of ovarian follicles, which has been associated with reversible infertility in some women. In women who have difficulties conceiving or who are undergoing investigation of infertility, withdrawal of NSAIDs, including topical piroxicam should be considered.

Piroxicam Use During In Pregnancy

The Safety of topical piroxicam use during pregnancy or during lactation has not yet been established.

There are no studies of the use of topical piroxicam in pregnant women. Studies in animals have shown reproductive toxicity with systemic formulations (see section Preclinical Safety Data), but their relevance to the use of topical formulations in pregnant women is unknown. As a precautionary measure, it is preferable to avoid the use of topical piroxicam in pregnant women.

Inhibition of prostaglandin synthesis might adversely affect pregnancy Data from epidemic biological studies suggest an increased risk of spontaneous after the use of prostaglandin synthesis inhibitors in early pregnancy. In animals, the administration of prostaglandin synthesis inhibitors shown to result in increased pre-and post-implantation loss.

Feldene Use During Lactation

Generally, Piroxicam topical not recommended for use in nursing mothers, as clinical safety has not established.

Feldene Gel Side Effects

Like all the medicine Feldene Cream Side effects possibly related to treatment infrequently reported. In clinical trials, the vast majority of side effects involved mild or moderate

• Firstly you may face local irritation
• Secondly, erythema also studied in some patients
• On the other hand, some rash cases also studied
• Similarly, some patients may also face pityroid desquamation
• Consequently, pruritus also shown in minor cases.
• Lastly, the reactions at the application site can also appear but only in some patients.

In Post Marketing experience, the following additional dermatological effects reported:

• Contact dermatitis
• Eczema
• Photosensitivity skin reaction

On the other hand, Mild but transient skin discoloration and staining of clothing noted when it not rubbed in completely.

Feldene Overdosage Symptoms & Treatment

Most importantly, the Overdosage is unlikely to occur with this topical preparation.

Feldene Cream Storage Instructions

Firstly, Close the cream well after you open the seal of the packing. Most importantly always keep the medicines out of the reach of your small children at home. On the other hand, you must protect this medicine product from direct sunlight and heat.

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Feldene (Piroxicam) Gel 25 G Cream Price