Kestine (Ebastine) Tablets
Kestine Tablets contains Ebastine which is a non sedating anti histaminic agent. Ebastine use for symptomatic relief of allergic conditions including allergic rhinitis and in pruritic skin disorders. On the other hand, Kestine Tablets may also use for flu-like symptoms. It does not have significant sedatives or antimuscarinic actions.
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Kestine Tablets Composition
- Kestine 10 mg tablets contains : Ebastine B.P. 10 mg.
- Kestine 20 mg tablets contains : Ebastine B.P. 20 mg.
- Kestine Liquid Each 5 ml contains : Ebastine B.P. 5 mg.
Kestine Tablets Uses
Kestine indicated in the symptomatic treatment of :
- Allergic rhinitis associated or not with allergic conjunctivitis.
- Idiopathic chronic urticaria.
- Allergic dermatitis.
Kestine Tablets Dosage And Administration
The Kestine Dosage should be used as under:
Kestine Uses In Allergic Rhinitis:
Firstly, the recommended dose is Kestine 10MG once daily. However, in the event of severe symptoms, the Kestine Dosage may increased to Kestine 20MG once daily. Furthermore, this can take as two doses of Kestine 10mg or as one dose of Kestine 20 mg.
Kestine Uses In Urticaria:
However, the adult doses is Kestine 10 MG orally daily. But, doctors or pharmacists may decide according to the patient’s condition.
Dosage For Allergic Dermatitis:
Furthermore, The adult Kestine dose is 10 mg of orally daily.
Kestine dosage of oral Liquid is:
Adults And Children Over 12 Years Of Age:
The recommended doses are Kestine 10MG once daily.
Children Aged 6 to 11 years:
Once doses of 5 ml kestine once day.
Children Aged 2 to 5 Years:
The usual doses are 2.5 ml kestine once a daily.
Children Under 2 Years Of Age:
Most importantly, the safety of Ebastine has not been established for children under 2 years of age.
Kestine Uses In Special Groups
Elderly Patients:
Lastly, It is not necessary to adjust the dose.
Hepatic Insufficiency:
However, It is not necessary to adjust the dose in patients with mild or moderate liver impairment. Meanwhile, there is no experience with doses over kestine 10 mg in patients with severe hepatic insufficiency. Therefore the dose of 10 mg kestine per day should not be exceeded in these patients.
Kestine Tablets Contra-Indications
Most importantly the medicine is contraindicated to Hypersensitivity to the active ingredient kestine.
Kestine Warnings And Precautions
- Most importantly, Caution should be taken when prescribing kestine tablets in combination with azole antimycotic agents. On the other hand, type ketoconazole and itraconazole, or macrolide antibiotics type erythromycin.
- On the other hand, Caution should be taken when kestine prescribing with drugs belonging to antituberculosis type rifampicin.
- Ebastine Tablet at recommended therapeutic doses does not affect the ability to drive or operate machines. However, insensitive subjects who react unusually to Ebastine Tablets. Therefore, It is advisable to known the individual reactions before patients drivers or carries out complicated activities.
- Meanwhile, the Patients with hereditary galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicinal product.
- This medicinal product may cause stomach upset and diarrhea because it contains polyethylene glycol.
- On the other hand, the Patient with a rare hereditary problems of fructose intolerance should not take this medication.
Kestine Drug Interactions
- Firstly, Pharmacokinetic interactions have been observed when Ebastine Tablet is given with ketoconazole or itraconazole and erythromycin. Meanwhile, These Interactions resulted in increased plasma concentrations of Ebastine.
- Secondly, Pharmacokintions interactions have been observed when Ebastine Tablets are given with rifampicin. However, These interactions could result in lower plasma concentrations and reduced antihistamine effects.
- Furthermore, No interactions have been reported between Ebastine Tablets and theophylline, warfarin, cimetidine, diazepam and alcohol.
Excipients For Kestine Liquid
- Glycerin
- Lactic Acid
- Sorbitol
- Methyl Paraben Sodium
- Propyl Paraben Sodium
- Neohesperidine Dihydrochalcone
- Polyoxyl 40 Hydrogenated Castor Oil
- Sodium Hydroxide
- Anethole
- Simethicone Emulsion
Excipients For Kestine Tablet
- Microcrystalline Cellulose
- Lactose
- Croscarmellose sodium
- Pregelatinized Starch
- Magnesium stearate
- Hydroxypropyl Methylcellulose
- Polyethylene Glycol (6000)
- Titanium Dioxide (Just in Kestine 20MG Only)
Ebastine Kestine Tablet Use In Pregnancy And Lactation
However, there are a limited amount of data from the use of Kestine Tablet Ebastine uses in pregnancy. As a precautionary measure, it is preferable to avoid the use of Ebastine during pregnancy. Therefore, It is not known whether Ebastine is excreted in human milk. However, As a precautionary measure, it is preferable to avoid the use of Ebastine during lactation.
Kestine (Ebastine) Side Effects
However, The commonly reported Kestine (Ebastine) Side Effects are dry mouth and somnolence. Meanwhile, The other reported adverse effects are
- Hypersensitivity Reactions
- Nervousness
- Insomnia
- Headache
- Dizziness
- Hypoesthesia
- Dysgeusia
- Palpitations
- Tachycardia
- Abdominal pain
- Urticaria
- Rash
- Dermatitis
- Menstrual disorder
- Edema,
- Asthenia
Most importantly, if you face any of the described kestine tablet side effects you may stop the medicine use and contact your doctor who will decide the further use of the medication.
Kestine (Ebastine) Overdosage
Meanwhile, there is no specific antidote for kestine. Gastric lavage, monitoring of vital functions including ECG and symptomatic treatment should be carried out. Most importantly, you must remember to reach the nearby hospital or immediately contact your doctor in case of any medication overdose.
Kestine (Ebastine) Storage Instructions
Firstly, Keep out of the reach of children. Most importantly, Store below 30 C in a dry place. On the other hand, Protect from sunlight and heat. Lastly, you must read the kestine pack for its expiry date. And if the product is expired you must not use it.
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Kestine (Ebastine) 10MG, 20MG Tablets