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Losec Tablet Omeprazole 10MG 20MG 40MG Uses Dosage Details

Losec Tablet: 10mg, 20mg and 40 mg contains the most famous medicine named Omeprazole. Omeprazole is an oral antiulcer agent. It is charactrized as a gastric acid pump inhibitor because it blocks the final step of gastric acid production. Meanwhile, it has a long duration of action and very potent, allowing for once daily administration.

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Formula Ingredients Composition

Each of the tab contains: Omeprazole 10mg, Omeprazol 20mg and Omeprazole 40mg.

Losec Tablet Omeprazole 10mg 20mg 40mg Uses & Indications

Losec (Omeprazole) Tablets indicated and used for the treatment of the symptoms Like

• Duodenal Ulcer
• Gastric Ulcer
• NSAID associated gastric and duodenal ulcers or erosions
• Helicobacter pylori eradication in peptic ulcer disease
• Reflux oesophagitis
• Symptomatic gastro oesophageal reflux disease
• Zollinger Ellison syndrome

Tab Losec Tablet Dosage And Method Of Administration

Losec capsules are recommended to use in the morning and swallowed whole with half a glass of water. On the other hand, The capsules should not be chewed or crushed. However, follow your pharmacist or doctors instruction to take the medicine.

Dosage For Patients With Swallowing Difficulties

However, it can be opened and the contents swallowed directly with half a glass of water or after mixing the contents in a slightly acidic fluid the e. g . fruit juice or applesauce or in non carbonated water. The dispersion should be taken immediate (or within 30 minutes ) always stir just before drinking. Meanwhile, Rinse it down with half a glass of water. On the other hand, such patients can also suck the tab and swallow the pellets with half a glass of water. However, Ingest without chewing the enteric coated pellets.

The Dosage Duodenal Ulcer

Meanwhile, The recommended dosage in patients with an active duodenal ulcer is losec 20 mg once daily. Therefore, Symptom resolution is rapid and in most patients healing occurs within 2 weeks. On the other hand, For those patients who may not fully healed after the initial course, healing usually occurs during a further 2 week treatment period. However, In patients with poorly responsive duodenal ulcer losec 40 mg once daily recommended. And after the treatment the healing normally gets within 4 weeks . Meanwhile, For the prevention of relapse the in patients with duodenal ulcer disease the recommended dose is losec 10 mg once daily. However, If needed the dose can be increased to 20-40 mg once daily for NSAID associated duodenal ulcer.

Dosage Gastric Ulcer

Meanwhile, the recommended 20 MG once daily. However, symptom resolution rapid and in most patients healing occurs within 4 weeks. However, for those patients who may not be fully healed after the initial course healing usually occurs during a further 4 weeks treatment period. Meanwhile, In patients with poorly responsive gastric ulcer 40 mg once daily is recommended. And healing is usually achieved within 8 weeks. However For prevention of relapse in patients with poorly responsive gastric ulcer the recommended dose is 20 mg once daily if needed. The dose van increased to 40 mg once daily.

NSAID Associated Gastric Ulcers Duodenal Ulcers Or Gastroduodenal Erosions In Patients With Or Without Continued NSAID Treatment

Meanwhile, The recommended Omeprazole dosage is 20 mg once daily. However, Symptom resolution is rapid and in most patients healing occurs within 4 weeks. Therefore, for those patients who may not be fully healed after the initial course healing usually occurs during a further 4 weeks treatment period. On the other hand, for the prevention of NSAID associated gastric ulcers duodenal ulcers gastroduodenal erosions. And dyspeptic symptoms the recommended dosage is 20 mg once daily .

Helicobacter Pylori (Hp) Eradication Regimens In Peptic Ulcer Disease

Triple Therapy Regimens:

20 mg amoxicillin 1 g and clarithromycin 500 mg. All twice a day for one week. Or 20 mg metronidazole 400 mg (or tinidazole 500 ) and clarithromycin 250 mg all twice a day for once week. Or 40 mg once daily with amoxicillin 500 mg and metronidazole 400 mg both three times a day for one week.
Dual Therapy Regimens:
40- 80 mg daily with amoxillin 1. 5 g daily in divided doses for two weeks. In clinical studies daily doses of 1.5-3 g of amoxicillin have been used. Or 40 mg once daily and claritromycin 500 mg three times a day for two weeks .

To ensure healing in patients with active peptic ulcer disease see further dosage recommendation for duodenal and gastric ulcer. In each regimen if the patient still hp positive therapy may be repeated.

Dosage For Reflux Oesophagitis

Meanwhile, The recommended dosage is 20 mg once daily. Normally the speed of treatment of symptoms is very quick and in most patients healing just occurs only within 4 weeks. For those patients who may not fully healed after the initial course healing usually occurs during a further 4 weeks treatment period. In patients with severe reflux oesophagitis 40 mg once daily recommended. And healing usually achieved within 8 weeks. For the long term management of patients with healed reflux oesophagitis the recommended dose 10 mg once daily. If needed the dose can increased once daily .

Dose For Symptomatic Gastro Oesophageal Reflux Disease

On the other hand, the recommended dosage is 20 mg daily. However, Symptom relief is rapid. Patients may respond adequately to 10 mg daily. And therefore individual dose adjustment should be considered. However, If symptom control has not achieved after 4 weeks treatment with 20 mg daily. Most importantly, further investigation recommended .

Dosage For Zollinger - Ellison Syndrone

Most importantly, In patients with zollinger-ellison syndrome the dosage should individually adjusted. And treatment continued as long as clinically indicated. Meanwhile, The recommended initial dosage is 60 mg daily. On the other hand, All patients with severe disease and inadequate response to other therapies have been effectively controlled. And more than 90% of the patients maintained. And doses of 20-120 mg daily when doses exceed 80 mg daily the dose should be divided and given twice daily .

Uses For Impaired Renal Function

Omeprazole (Losec) Capsules Dose adjustment not needed in patients with impaired renal function

Dosage In Impaired Hepatic Function

In patients with impaired hepatic function a daily dose of 10-20 mg may sufficient.

Dosage For Adults(>65 years old)

Generally Dosage adjustment mainly not needed in the treatment for adults.

Dosage For Child

10 mg 20 mg and 40 mg capsules not approved for use in children .

Contraindications For The Use Of This Medicine

Most importantly, the Losec Medicine is contraindicated in the patients who are Hpersensitivily to omerprazole substituted benzimdazoles or to any of the excipients. Meanwhile, Omeprazole like other proton pump inhibitors (PPIs) must not used concomitantly with nelfinavir.

Omeprazole (Losec) Use During Pregnancy And Lactation

Pregnancy well conducted epidemiological studies indicate no adverse effects of omeprazole on pregnancy. On the other hand, on the health of the fetus newborn child. Meanwhile, the drug can used during pregnancy. However, it may excreted in breast milk influence if any on the child unknown.

Effects On Ability To Drive And Use Machines

Meanwhile, Tab Losec is not likely to affect the ability to drive or use machines.

Losec (Omeprazole) Tablet Side Effects

However the medicine is well tolerated but the most common Losec Tablet (Omeprazole) side effects 1-10 of patients are:

• Headache
• Abdominal pain
• Constipation
• Diarrhoea
• Flatulece and
• Nausea
• Vomiting

Most importantly, The following adverse reactions have identified or suspected in the clinical trials program for Omeprazole and post marketing. However, None found to dose related adverse reactions listed below classified according to frequency and system organ class Soc. Most importantly, If you observe any of the side effects after using the medicine you must immediately contact your doctor or pharmacist.

Losec (Omeprazole) Tablets Capsules Side Effects

 

• Blood And Iymphatic System Disorders

Rare: Leukopenia, Thrombocytopenia

Very Rare: Agranulocytosis, Pancytopenia

• Immune System Disorders

Rare: Hypersensitivity Reactions Like, Fever, Angioedema, Anaphylactic Reaction or Shock

• Metabolism And Nutrition Disorders

Rare: Hyponatraemia

Very Rare: Hypomagnesaemia

• Psychiatric Disorders

Uncommon: Insomnia

Rare: Agitation, Confusion, Depression

• Nervous System Disorders

Common: Headache

Uncommon: Dizziness, Paraesthesia, Somnolence

Rare: Taste Disturbance

• Eye Disorders

Rare: Blurred Vision

• Ear & Labyrinth Disorders

Uncommon: Bronchospasm

• Respiratory, Throacic & Mediastinal Disorders

Rare: Bronchospasm

• Gastrointestinal Disorders

Common: Abdominal Pain, Constipation, Diarrhoea, Flatulence, Nausea, Vomiting

Rare: Dry Mouth, Stomatitis, Gastrointestinal Candidiasis

• Hepatobiliary Disorders

Uncommon: Increased Liver Enzymes

Rare: Hepatitis With or Without Jaundice.

Very Rare: Hepatic Failure, Encephalopathy in Patients with pre-existing liver disease.

• Skin And Subcutaneous Tissue Disorders

Uncommon: Dermatitis, Pruritus, Rash, Urticaria

Rare: Alopecia, Photosensitivity

Very Rare: Erythema Multiforme, Stevens Johnson Syndrome, Toxic Epidermal Necrolysis

• Musculoskeletal And Connective Tissue Disorders

Rare: Arthralgia, Myalgia

Very Rare: Muscular Weakness

• Renal And Urinary Disorders

Rare: Interstitial Nephritis

• Reproductive System And Breast Disorders

Very Rare: Gynaecomastia

• General Disorders And Administration Site Conditions

Uncommon: Malaise, Peripheral Oedema

Rare: Increased Sweating

Medication Overdose Symptoms & Treatment

Limited information available about the Losec Omeprazole tablets overdose side effects and symptoms in humans. Furthermore, it reported that the doses of up to 560 mg have described. And occasional reports received when single oral doses have reached up to 2,400 mg drug. Nausea vomiting dizziness abdominal pain diarrhoea and headache have reported. On the other hand, apathy, depression and confusion side effects have also reported the overdosage symptoms in single cases.

The symptoms described have transient and no serious outcome has reported. The rate of elimination unchanged first order kinetics with increased doses treatment if needed is symptomatic.

Storage Instructions

Most importantly keep all the tablets, injections, syrups out of the reach of the children. On the other hand, Do not store Losec Tablets (Omeprazole Capsules) over 30 C temperature. Meanwhile protect the medical products from direct sunlight and heat.

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Losec (Omeprazole) 10MG, 20MG, 40MG Tablets Price (Rs. 733 PKR) & $ 6 USD In USA