Sakoon Tablets (Bromazepam) 3MG Uses Dosage Side Effects
Sakoon Tablets contains Bromazepam. Bromazepam is a benzodiazepine with general properties similar to those of diazepam. And Bromazepam used in the treatment of anxiety and as a hypnotic.
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Sakoon Tablets (Bromazepam) Dosage
The maximum recommended Bromazepam Dosage is Sakoon Table 60 mg daily.
Average Bromazepam Dose For Ambulatory: Sakoon Tablets (Bromazepam) 3mg two or three times in divided doses daily. It is often an advantage to make the evening dose larger other doses. Or when the total Bromazepam Dose is low e.g to give the total dose in the evening .
Severe Hospitalized Cases: Bromazepam 6mg to 12mg two or there time daily. These amounts are general recommended , and dosage should individually determined . Treatment of out patients should started with low bromazepam doses which gradually increasing to the optimum level . When treatment is ceased withdrawal should gradual. The Sakoon Medicine duration of treatment should be as short as possibly can. The patients should reassessed regularly and the need for continued treatment should evaluated . The overall treatment should not more than 2 to 4 weeks followed by a tapering off process of up to 6 to 8 weeks .
Special Dosage Instruction: Bromazepam 3 MG is not recommended in children as there is insufficient evidence safety and effects in this group Elderly patients and those with impaired hepatic function may require lower dose . Furthermore, the professional doctor or pharmacist may decide the exact dosage for the patient according to the one’s condition.
Sakoon Tablets Contraindications
Sakoon Tablets contraindicated in patients with the following symptoms:
- Known hypersensivity to benzodiazepines
- Severe respiratory insufficiency , including chronic obstructive airways disease with incipient respiratory failure
- Hepatic insufficiency as it may cause encephalopathy
- Sleep apnea syndrome
- Myasthenia gravis
Sakoon Tablets Precautions
Medical History Of Drinking Abuse: Patients checked regularly at the start of treatment in order to minimize the dosage. And the frequency of administration, and to prevent overdose due to accumulation of Bromazepam. Patients with known or presumed dependence on Drinks should not take Bezodiazepines unless under medical supervision.
Concomitant Use Of Drinks CNS Depressants: Patients should advised that their tolerance for drinks and other CNS depressants will be diminished. And concomitant use of Sakoon Tablets and drinks should avoided. Such concomitant use has the potential to increase the clinical effects of Sakoon 3MG. which possibly may including symptoms like severe sedation, clinically relevant respiratory and or cardiovascular depression.
Sakoon (Bromazepam 3MG) Medicine Duration Of Treatment
In general benzodiazepines should prescribed for short periods only like 2 to 4 weeks. However, Continuous long term use of Sakoon Tablets not recommended. Therefore evidence that tolerance develops to the sedative effects of benzodiazepines . After as little as one week of therapy withdrawal symptoms can appear following the cessation of recommended doses Like. rebound insomnia following cessation of a hypnotic benzodiazepine. However, Following the prolonged use of Sakoon 3 MG at therapeutic doses withdrawal from the medical product should gradual. An individualized withdrawal timetable needs to be planned for each patients in whom dependence known or suspected. Periods from four weeks to four months have been suggested . As with other bezodiazepines, when treatment suddenly withdrawn, a temporary increase in sleep disturbance can occur after use of Bromazepam Tablets 3MG .
Bromazepam 3MG In Hypotension
Although hypotension has occurred rarely but Sakoon Tablets should administered with caution to patients in whom a drop in blood pressure might lead to cardiac or cerebral complications. Therefore, This is particularly important in Elderly patients for the use of this medicine.
Sakoon 3MG In Amnesia
Transient amnesia or memory has been reported in association with the use of benzodiazepines. Therefore, Anterograde amnesia may occur at therapeutic dosage with the risk increasing at higher dosage. Meanwhile, Amnesiac effects may be associated with inappropriate behavior.
Myasthenia Gravis
Sakoon Tablets could increase the muscle weakness in myasthenia gravis and should not be used in patients with this condition.
Acute Narrow Angle Glaucoma
Most importantly, Caution should used increase the treatment of patients with acute narrow angle glaucoma because of atropine like side effects.
Impaired Renal Live Function nd Blood Dyscrasias
Firstly, Patients with impaired renal or hepatic function should use bezodiazepine medical product with caution and dosage reduction may be advisable. However, In rare instances some patients taking benzpdiazepine have developed blood dyscrasias and some have had elevation of liver enzymes. Therefore, As with other benzodiazepines , periodic blood ccunts and liver function tests recommended .
Depression Psychosis And Schizophrenia
Sakoon 3MG not recommended as primary in therapy patients with depression, anxiety and psychosis. In such conditions, psyhiatric assessment and supervision necessary if benzodiazepine indicated. Meanwhile, Benzodiazepines (Sakoon Tablet) may increase depression in some patients and may contribute to deterioration in disturbed schizohernics with confusion and withdrawal. On the other hand, Preexisting depression may be unmasked during benzodiazepine use. Therefore, Suicidal tendencies may be present or uncovered and protective measures may be required .
Paradoxical Reactions
In Addition, Paradoxical reactions Like
- Restlessness
- Agitation
- Irritability
- Rages hallucination
- Aggressiveness
- Delusion nightmare
- Psychoses inappropriate behavior.
And other adverse behavioral acute rage, stimulation excitement may occur, should such reaction occur, Sakoon should discontinued .
Impaired Respiratory Function
Most importantly, Bromazepam 3MG Tablets should be used with extreme caution in patients with respiratory depression. However, In patients with chronic obstructive pulmonary disease , bezodiazepine can cause increased arterial carbon dioxide tension and decreased oxygen tension.
Epilepsy
When Sakoon 3 MG administered to persons with convulsive disorder, an increased in the frequency and severity of grand seizures may occur necessitating increased anticonvulsant medication. Therefore, About withdrawal of benzodiazepines in persons with convulsive disorder may associated with a temporary increase in the frequency and severity of seizures.
Hereditary Problems
As Sakoon Tablets contains lactose a well known drug. So the patients with hereditary problems Like
- Galactose intolerance
- Lapp lactase deficiency
- Glucose galactose malabsorption should not take this tablet .
Sakoon Tablets During Pregnancy
However, Category C benzodiazepines cross the placenta and may cause hypotonia , reduced respiratory function and hypothemia in the newborn infant. But Continuous Bromazepam 3MG Tablets treatment during pregnancy and administration of Bromazepam high doses in connection with delivery should avoided. Ont the other hand, Withdrawal symptoms in newborn infants reported with this class of medical product. And may at some risk for developing withdrawal symptoms in the postnatal period . However, If Sakoon prescribed to a woman of childbearing potential, she should warned to contact her physician regarding discontinuing sakoon. If she intends to become , or suspects that she has pregnancy .
Effects On Ability To Drive And Use Machines
As with all patients who used CNS depressant type of medicines patients receiving Sakoon, should warned not to operate dangerous machinery or motor vehicles unite it known that they do not become drowsy or dizzy from therapy. Sedation, amnesia muscular function may adversely affects the ability to drive or operate machinery. This increased if the patients has taken drinks concomitantly with sakoon. However, Abilities may impaired on the day following use .
Bromazepam Side Effects
Psychiatric Disorders:
- Confusional State
- Emotional Disturbance
- Libido Disorders
- Nervousness And Depression
- Paradoxical reaction
- Restlessness
- Agitation
- Irritability
- Aggression
- Delusion
- Anger
- Nightmares
- Sleep Disorders
- Hallucinations
- Phychosis
- Inappropriate Behavior
If these Bromazepam Side Effects occur, the use of Sakoon Tablets should discontinued. Therefore, Such reactions are more likely to occur in children and elderly patients than in other patients .
Dependence Of This Medicine
Chronic use may lead to the development of physical and psychic tablet dependence. Meanwhile, Discontinuation of therapy may result in withdrawal or rebound phenomena abuse of benzodiazepines has been reported.
Nervous System Disorders
However, There are some reports of drowsiness and ataxia in some patients become less common with repeated administration. On the other hand, Headache, dizziness, decreased alertness, seizures, tremor, speech and incontinence. Meanwhile, Anterograde amnesia may occur using therapeutic dosage with the risk increased at higher dosage. On the other hand, Amnestic effects may associated with inappropriate behavior.
Eye disorders:
- Diplopia
- Blurred vision .
Gastrointestinal Disorders:
- Gastrointestinal Disorders
- Dry Mouth
- Nausea
- Vomiting
Metabolic And Nutritional Disorders:
- Anorexia
Skin And Subcutaneous Tissue Disorders:
- Skin reactions
- Pruritus
- Rash
Musculoskeletal And Connective Tissue Disorders:
- Muscle Weakness
- Muscle Spasm
Respiratory Disorders:
- Respiratory Depression
Cardiac Disorders:
- Hypotension
- Cardiac Failure
- Cardiac Arrest
- Tachycardia
- Palpitations
Investigations:
Instances of decreased haemoglobin and increased white cell counts.
Bromazepam Overdose Symptoms & Treatment
Bromazepam Overdose Symptoms:
Firstly, Overdosage of benzodiazepines usually manifested by degrees of central nervous system depression ranging from drowsiness to coma. On the other hand, In mild cases symptoms include drowsiness, mental confusion and lethargy .
Therefore, Overdose of Sakoon 3 MG Tablets seldom life threatening if the tablet is taken alone. But may lead to areflexia, apnea, ataxia, hyptonia , hypotension, cardio respiratory depressant and coma. On the other hand, Coma may more protracted and cyclical. Particularly in elderly patients benzodiazepines respiratory depressant effects are more serious. Meanwhile, Patients with respiratory disease benzodiazepines increase the effects of the other central nervous system depressants , including drinking . When combined with other CNS depressants the effects of Bromazepam 3MG Overdose are likely to be severe and may prove fatal.
Bromazepam Overdose Treatment:
Meanwile, Bromazepam 3MG Treatment of overdose is symptomatic institute supportive measures as indicated by the patients clinical state. However, If the over-dosage known to be small, observation of the patient and monitoring of their vital signs only may appropriate in adult or children. Who have taken an overdose of benzodiazenpines within 1 to 2 hours, consider activated charcoal with airway protection if indicated. Therefore, If CNS depression is severe consider the use of flumazenil, a benzodiazepine antagonist. Most importantly, this should only administered under closely monitored conditions. It has a short half life about an hour therefore patients administered flumazenil will require monitored after its effects have worn off. On the other hand, Flumazenil is to be used with extreme caution in the presence of medical product that reduce seizure threshold Like. tricylic antidepressants, Haemoperfunsion and haemodialysis not useful in benzodiazepine intoxication.
Sakoon Storage Instructions
Most importantly always keep all the tablets, syrups, injections out of the reach of the children. On the other hand, Store the tablets under 30 C temperature and protect from sun light and moisture. Lastly, you must not use the medicine after the expiry date mentioned on the pack.
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Sakoon (Bromazepam 3MG) Tablets