Zantac Tablets 150MG 300MG Injections Uses Side Effects Price

Zantac Tablets Ranitidine 150 MG, 300 MG 500 MG & Injections Uses Dosage Side Effects Details

Zantac Tablets contains a useful medicine to reduce the stomach acid in humans named Ranitidine.

Zantac Tablets 150MG 300MG Injections Uses Dosage Side Effects Benefits Formula Ingredients Price
Ranitidine Zantac Tablet 150MG 300MG 500MG

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What Is Ranitidine And What It Used For?

Ranitidine is a histamine H-2 Receptor antagonist (AKA H2 Blocker). Which is very similar to cimetidine and famotidine drugs . Meanwhile Zantac (Ranitidine) is administered by orally in tablets form or through injection or infusion. It generally help to reduce the acidity in human stomach and relief the symptoms like ulcers etc. Mean while the medication sold under different brand names world wide like Zantac, and more. Most importantly, it first discovered in England in year 1976. However, it first approved to use in medicines in USA in year 1981.

Zantac Tablets Ingredients Formula Composition
  • Tablets:           Each Tablet contains Ranitidine (as HCL BP)150 mg or 300 mg.
  • Injection:         Each Injection 2ml contains 50mg Ranitidine as Ranitidine hydrochloride BP.

Zantac Tablets, Injections Uses & Indications

Ranitidine, Zantac Tablets Uses in Adults / Adolescents (12 year and over)

 Oral Formulation:

  • Duodenal ulcer and also used in benign gastric ulcer, including the symptoms that associated with non-steroidal anti-inflammatory agent.
  • Zyntac Tablet also used for the prevention of non-steroidal anti-inflammatory Tablet (NSAID) (including aspirin) associated duodenal ulcer, especially in patients with a history of peptic ulcer disease.
  • Duodenal ulcer associated with Helicobacter pylori infection.
  • Post-operative ulcer.
  • Reflux esophagitis.
  • Zantac Tablet use for the symptom relief in gastro-esophageal reflux disease.
  • Also used for the symptoms of Chronic episodic dyspepsia, characterized by pain (epigastric or retrosternal). Which related to meals or disturbs sleep but not associated with the above conditions.
  • On the other hand, Prophylaxis of stress ulceration in seriously ill patients.
  • Prophylaxis of recurrent hemorrhage from peptic ulcer.
  • Zyntac tablets also use for the treatment of Zollinger-Ellison Syndrome.
  • Prophylaxis of Mandelson’s syndrome.

Zantac Injection Uses:

  • Duodenal ulcer.
  • Benign gastric ulcer.
  • Post-operative ulcer.
  • Reflux esophagitis.
  • Prophylaxis of stress ulceration in seriously ill.
  • Zollinger-Ellison Syndrome.
  • Prophylaxis of recurrent hemorrhage from peptic ulcer.
  • Prophylaxis of Mendeison syndrome.
Zantac Tablets 150MG 300MG Injections Uses Dosage Side Effects Benefits Formula Ingredients Price
Ranitidine (Zantac) Injection Uses Dosage Side Effects
Zantac (Ranitidine) Tablets Uses in Children / Infants (1 month to 11 years)

Oral Formulation:

  • It used for the treatment of peptic ulcer.
  • Zantac uses for the treatment of gastro-esophageal reflux-including reflux esophagitis and symptom relief of gastro-esophageal reflux disease.

Zantac (Ranitidine) Injection Uses:

  • Injection Zyntec uses for the treatment of peptic ulcer
  •  Injection use for the treatment of gastro esophageal reflux including reflux esophagitis and symptom relief of gastro esophageal reflux disease
  • Prophylaxes of stress ulceration in seriously ill patients
  • Duodenal ulcer and benign gastric ulcer acute treatment

Zantac (Ranitidine) Tablets Injections Dosage Administration

Ranitidine Use in Duodenal Ulcer And Benign Gastric Ulcer:

Acute Treatment

Meanwhile, The standard dosage regimen for duodenal or benign gastric ulcer is 150mg twice daily or 300mg once nightly. But In most Cases of duodenal ulcer or benign gastric ulcer healing occurs within 4 weeks. On the other hand, Healing usually occurs after a further 4 weeks in those not fully healed after the initial 4 weeks. Meanwhile, In duodenal ulcer Ranitidine 300mg twice daily for 4 weeks with 150mg twice daily, or 300mg once nightly. Therefore, The increased dose has not associated with an in creased incidence of unwanted effects Zantac (Ranitidine) Long Term Use: For long term use management of duodenal or benign gastric ulcer dosage regimen is 150mg once nightly. On the other hand, Smoking is associated with a higher rate of duodenal ulcer relapse. And such patients should advised to stop smoking. However, In those who fall to comply with such advice a dosage of Zantac 300mg once nightly provides additional therapeutic benefit over the 150mg  dosage regimen.

NSAID Associated Peptic Ulceration

Acute Treatment

Meanwhile, In ulcer following non steroidal inflammatory medical therapy or associated with continued non-steroidal anti-inflammatory tablets. Therefore, 8 to 12  weeks treatment may necessary with Tablet 150mg twice daily or Tablet 300 mg once nightly. Duodenal Ulcer Associated With Helicobacter Pylori Infection Tablet 300 mg once nightly or Tablet 150mg  twice daily may be given with oral amoxicillin 750 mg 3 times daily. And metronedazowle 500 mg 3 times daily for 2 weeks. Most importantly, it should continue for a further 2 weeks. Therefore, This dose regimen significantly reduces the frequency of duodenal ulcer recurrence. Post Operative Ulcer The standard dosage regimen for post operative ulcer is Ranitidine 150 mg tablet twice daily. Most importantly in cases heal within 4 weeks. Meanwhile, Those not fully healed after the initial 4 weeks usually do so after a further 4 weeks.

Gastro Esophageal Reflux Disease

Acute Treatment: In reflux esophagitis Zintec 150 mg tablet twice daily or tablet 300 mg once nightly is administered for up to a period of 8 or if necessary 12 weeks. Therefore, In patients with moderate to severe esophagitis the dosage of this medication may be increased to 150 mg 4 times daily for up to 12 weeks. Long Term Management Most importantly, For the long term management of reflux esophagitis the recommended adult oral dose is 150 mg twice daily. Symptom Relief For the relief of symptoms associated with esophageal acid reflux. So, The recommended regimen is 150 mg twice daily for 2 weeks. Therefore, this regimen may continued  for a further 2 weeks  in those  patients in those patients in whom  the initial response is inadequate.

Zollinger Ellison Syndrome

The initial dosage regimen for Zollinger Ellison syndrome is 150 mg 3 times daily. But this may be increased as necessary. Meanwhile, the dosage up to 6 g per day have been well tolerated.

Chronic Episodic Dyspepsia

In addition the standard dosage regimen for with chronic episodic dyspepsia in 150 mg twice daily for up to 6 weeks. However, Anyone not responding or relapsing shortly afterwards should be investigated.

Prophylaxes Of Mendelson’s Syndrome

150mg 2 hours before anesthesia and preferably 150 mg the previous evening. Alternatively the injection is also available. However, In obstetric patients in labor 150 mg every 6 hours. But if general anesthesia is required it is recommended that a non particulate antacid given in addition.

Prophylaxis Of Haemorrhage From stress Ulceration In Seriously Ill Patients Or Prophylaxis Of Recurrent Hemorrhage In Patients Bleeding From Peptic Ulceration

It also use In the prophylaxis of hemorrhage caused from stress ulceration in seriously ill patients. Or prophylaxis of recurrent hemorrhage in those patients who have bleeding from peptic ulceration, parental administration must continued until oral feeding commences. Meanwhile, Patients considered to be at risk may then be treated with zantac tablet uses 150 mg twice daily . However, In the prophylaxis of upper gastrointestinal hemorrhage from stress ulceration in seriously ill patients. Therefore,  A priming dose of 50 mg as a slow i.v. injection followed by a continuous i.v. infusion of 0.125-0.250 mg/kg/h may be preferred.

Children Infants (1 month to 11 years)

Oral Formulations  Peptic Ulcer Acute treatment The recommended oral dose for  the treatment of peptic ulcer in children is 4 mg/kg/day to 8 mg/kg/day. So, it administered  as two divided doses to a maximum of 300 mg per day. Most importantly, For those patients with incomplete healing another 4 weeks of therapy is indicated as healing usually occurs within 8 weeks of treatment.

Gastro Esophageal Reflux

However, The recommend oral dose for the treatment of gastro esophageal reflux in children is 5/mg/kg/day to 10 mg/kg/day. Therefore, it Administered as two divided doses to a maximum of 600 mg zantac per day.

Peptic Ulcer Acute Treatment For Peptic Ulcer And Gastro Esophageal Reflux

Most importantly, the recommended i.v. dose for the treatment for peptic ulcer and gastro esophageal reflux in children is 2 mg/kg/day to 6 mg/kg/day administered as two to four divided doses. Therefore, this recommendation is derived from adult clinical studies and pharmacokinetic data in child patients.

Prophylaxis Of Stress Ulceration In Seriously Ill Patients

Most importantly, The recommended i.v. dose for prophylaxis of stress ulceration in seriously ill patients is 2 mg/kg/day to 6 mg/kg/day. Meanwhile, it administered as two four divided doses. Alternatively this medicine may administered for prophylaxis of stress ulceration in serious ill patients by continuous infusion.

Zantac During Pregnancy And Lactation

Fertility: There are data on the effects of the medication on human fertility. However, There were no effect on male and female fertility in animal studies. But, you may contact your doctor if you are pregnant or planned to get pregnant because he may decide about the medicine uses. Ranitidine During Pregnancy And Lactation Meanwhile, it crosses the placenta and is excreted in breast milk. Like other products tablets or capsules should only used during pregnancy or during breast feeding if considered essential. However, only an expert doctor can suggest the medicine usage during lactation.

Zantac Side Effects

Blood & Lymphatic System Disorders

Very Rare:    Blood count changes (leucopenia, thrombocytopenia). However, these are usually reversible.  On the other hand, Agranulocytosis or pancytopenia sometimes with marrow hypoplasia or marrow aplasia.

Immune System Disorders

Rare:   Hypersensitivity reactions (urticaria angioneurotic oedema fever bronchospasm hypotension and chest pain Very Rare:     Anaphylactic shock There  have reported after a single dose.

Psychiatrics Disorders

Very Rare:      Reversible mental confusion, depression and hallucinations These  Side Effects have  reported predominantly in severely ill and elderly patients

Nervous System Disorders

Very Rare:      Headache sometimes severe  dizziness and reversible involuntary movement disorders

Eye Disorders

Very Rare:      Reversible blurred vision There have been report of blurred vision after the use Use which is suggestive of a change in accommodation.

Cardiac Disorders

Very Rare:       As with other H2 receptor antagonists bradycardia, A.V block and with the injection only asystole.

Vascular Disorders

Very Rare:      Vasculitis

Hepatobiliary Disorders

Rare:      Transient and revers changes in liver function tests. Very Rare :     Hepatitis (hepatocellular,  hepatocanalicular or mixed) with  or without jaundice, these Zantac Side Effects are usually reversible.

Skin & Subcutaneous Tissue Disorders

Rare:      Skin rash Very Rare:       Erythema Multiforme, Alopecia.

Musculoskeletal & Connective Tissue Disorders

Very Rare:      Musculoskeletal symptoms such as arthralgia and myalgia.

Renal & Urinary Disorders

Very Rare:        Acute interstitial  nephritis.

Reproductive System & Breast Disorder

Very Rare:       Reversible impotence, breast symptoms and breast conditions such as gynecomastia and galactorrhea.

Zantac (Ranitidine) Overdose

However, this medication is very specific in action and no particular problems are expected following overdose with capsules formulations. Meanwhile, Symptoms and supportive therapy should be given as appropriate. So, you must contact your doctor or visit the nearby hospital in case of any over dosage.

Zantac Ranitidine Tablets Storage Instructions

Most importantly, keep all the Tablets out of the reach of the children to protect any threats to their life. On the other hand, Protect Zantac capsule/injection from direct sun light and heat. Therefore, store the Tablets under 30 C temperature. Lastly always check the zyntec medicine packing for its expiry date printed on each pack and if expired do not use it.

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Zantac Ranitidine 150 mg, 300 mg, 500 mg, 2ml Injection Price In Pakistan India USA

 

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Disclaimer

All the information about product uses, dosage side effects, formula, ingredients, indications, contraindications, drug interactions, warnings & precautions as well as it’s safe to use during pregnancy and lactation is purely based on the information available on the internet. And it is only provided here for general education and information purposes only. So do not take action about any of the information you found here because we do not guarantee the authenticity of each and every piece of information available on this website. All the information we produced is purely based on FDA-approved literature and does not substitute professional medical advice. This information is not intended to substitute medical advice, diagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical condition.

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