Zoloft 25MG 50MG Tablets Uses Dosage Side Effects Details
Are you facing any type of depression, or anxiety disorders or any other related symptoms? Zoloft 25MG and 50MG tablets are here to use for those who suffer from any disorders of depression, anxiety, psychiatric disorders, or the obsessive compulsive disorders. It main contains one of the best anti depressant medication named Sertraline Hydrochloride in it. It generally belongs to the drug class of selective serotonin reuptake inhibitors medicines. Pfizer the famous USA based pharmaceutical pharmacy company has first found this medication in year 1979. However it first approved to use in medicines in United States Of America in year 1991. In year 2022 it is the most recommended psychiatric medication by the doctors and pharmacist in USA with nearly over 40 million users in the year.
Zoloft 25MG 50 MG Tablets Combination Formula Ingredients
- Each 25 MG Tab Contains = Sertraline HCL USP 25MG
- Each 50MG Tab Contains = Sertraline HCL USP 50 MG
- 100MG Each Tab Contains = Sertraline HCL USP 100 MG
Zoloft 25MG 50MG 100MG Tablets Uses & Indications
As a best effective antidepressant medicine it raise the serotonin levels in the human brain and hugely improve the human mood in quick time. Mostly it recommended to use for the treatment of symptoms of depression including the symptoms of depression accompanied by symptoms of anxiety in patient with or without a history of mania. Following the satisfactory response the continuation with treatment of this medicine is effective in preventing relapse of the initial episode of depression of recurrence of further depressive episodes in such patients.
Its also indicated for the treatment of patients facing the obsessive compulsive disorders with following initial response it has been associated with sustained efficacy and tolerability up to 2 years of treatment of OCD. In the mean time doctors and pharmacist also recommend the use of Zoloft Medicine for the treatment of panic disorders with or without acrophobia, the society anxiety disorders and also for the post traumatic stress disorders. Meanwhile it also used for the treatment of several disorders like
- Depression or Major type of depressive disorders
- Obsessive compulsive disorders
- Panic Disorders
- Feeling angry, restless, irritable or agitated
- Post Traumatic stress disorders
- Worst type of panic attacks
- Premenstrual dysphoric symptoms
- Social anxiety disorders
- Unusual mood and behavior changes
- Premenstrual dysphoric disorders
- Sleep and Eat disorders
- Suicidal thinking symptoms
Medicine Pharmacokinetics Details
When using the multiple oral once daily dose of 200mg the mean peak plasma concentration of sertraline medications is 0.19 mcg/ml occurring between 6 to 8 hours post dose. On the other hand, following the single or multiple oral once daily doses of 50 to 400 mg/day. The average terminal elimination half life is approximately 26 hours or more. Moreover this medicine extensively metabolized to N-desmethylsertraline which shows negligible pharmacological activities. Both sertraline and N desmethylsertraline undergo oxidative deamination and subsequent reduction, hydroxylation and glucuronide conjugation. The biliary excretion of the metabolites is much significant in patients. Meanwhile, it bound nearly 98% of sertraline in plasma proteins.
Zoloft 25 MG 50 MG 100 MG Tablets Capsules Contraindications Details
Those people who have the hypersensitivity issues with Sertraline medication should not use the medicine. On the other hand its use with MAO inhibitors also contraindicated because it may cause the risk of serotonin syndrome in such patients. Most importantly if its necessary to use MAO inhibitors you should discontinue the use of this medicine and there must be a gap of 14 days or more before you start the MAO inhibitors.
Zoloft Dosage Information
Dosage For Adults
- Dose For Depression
The usual initial dose is 50mg daily and afterwards if the desired result not getting it may increased in increments of 50mg with equally divided intervals of at least a week to the maximum of 200 mg per day. If you consider to use it on the best time of the day to take zoloft for anxiety than just take it when you feel the symptoms are appearing in the patients.
Dosage For Obsessive Disorders
Initial recommended dose is a tab of 50mg per day only. However your doctor or pharmacist may decide whether or not to increase the dose according to the symptoms of an individual patient.
Dose For Panic Disorders
For the treatment of panic disorders in the patients with or without agoraphobia and post traumatic stress disorders. The usual initial lowest dose of zoloft is 25mg daily and increased after one week to 50mg daily only only if required.
Dosage Instructions For Children
The children age from 6 years to 1`2 years the usual initial dose is 25mg once daily only. Adolescents patients may given the dose up to 50mg per day. The dose may increased if necessary in increments of 50mg at intervals of at least a week to a maximum of 200mg daily. The lower body weight of child should be regularly observed in order to avoid excessive doses use. As with many other medications this tab should used with caution in patients with renal and haptic impairment.
Maintenance Dose For Patients
When a satisfactory clinical response has achieved in the patients the dosage should reduce to half of the medicine you previously used. And bring it to the minimum dose which maintain and relief the symptoms in specific patient.
Zoloft 25MG 50MG 100 MG Tablets Side Effects
Generally patients did not get any type of severe side effects symptoms after the use of this product. However the noticed side effects some patients may face in the first week of its use contains symptoms like weight gain and
Gastrointestinal complaints
- Nausea
- Diarrhea
- Loose stools
- Dyspepsia
- Male Dysfunction
- Insomnia
- Somnolence
- Tremor
- Increased sweating
- Dry mouth
- Dizziness
Autonomic Nervous System Disorders
- Infrequent flushing
- Mydriasis
- Increased saliva
- Cold clammy skin
Cardiovascular Side Effects
- Palpitations
- Chest pain
- Postural dizziness
- Hypertension
- Hypotension
- Postural hypotension
- Edema
- Dependent edema
- Periorbita edema
- Peripheral edema
- Peripheral ischemia
- Syncope
- Tachycardia
Rare Side Effects
- Precordial chest pain
- Substernal chest pain
- Aggravated hypertension
- Myocardial infraction
- Cerebrovascular effects
Skin And Appendages Side Effects
- Acne
- Alopecia
- Pruritus
- Erythematous rash
- Maculopapular rash
- Dry skin
- Photosensitivity reactions
Rare Side Effects
- Bullous eruption
- Dermatitis
- Hypertrichosis
- Follicular rash
- Skin discoloration
Endocrine Disorders
- Exophthalmos
- Gynecomastia
Muscle Skeletal System Disorders
- Arthralgia
- Arthrosis
- Dystonia
- Muscle cramps
- Muscle weakness
Zoloft Reproductive Side Effects In Women
- Dysmenorrhea
- Intermenstrual bleeding
- Balanoposthitis
- Chest enlargements
- Breast pains
- menorrhagia
- Atrophic Vaginitis
What Is Considered A High Dose Of Zoloft, Overdosage Symptoms & Treatment Guidelines
If the dose of zoloft over 200mg used per day considered as the highest dose may sometimes cause overdosage symptoms and it should need the proper medical intensions. The most common signs and symptoms associated with non fatal overdose were serotonin mediated side effects such as
- Somnolence
- Vomiting
- Tachycardia
- Nausea
- Dizziness
- Agitation
- Tremor
If you face any of the above said symptoms it may be because of any type of overdose of the sertraline hydrochloride medicine. And there are no specific antidotes for the overdose of this medicine. Therefore establish and maintain an airway, insure the adequate oxygenation and ventilation for the patients to breath easily. On the other hand activated charcoal which may used with sorbitol may be as or more effective than emesis or lavage. And it should considered in treating overdose with this medication. Cardiac and vital signs monitoring are recommended along with general symptomatic and supportive measure’s. Due to the large volume of distribution of Sertraline forced diuresis, dialysis, hemoperfusion and exchange transfusion are unlikely to be of benefits. In managing the overdose patients the possibility of multiple drug involvement must be also considered as a main fact.
Sertaline HCL Tablets Capsules Storage Instructions
Do not use the medicine by your own and it should only used after the advice of an expert doctor or pharmacist only. On the other hand check the packing for its expiry date which printed on each pack and if its expired do not use it. Store the medicine below 30C temperature and also protect it from direct sun light and heat exposures. Lastly always keep it out of the reach of your small kids at home as it may create several complication to their health.
Zoloft (Sertaline HCL) Tablets 25MG 50MG Capsules 100MG Price (Rs. 815 PKR) And In USA $ 200 USD