What Is Kestine (Ebastine) Tablets Uses, Is It Good For Itching?
Kestine Tablets are mainly composed of a useful medicine named Ebastine in its formula combination. It is mainly a second-generation nonsedating anti histamine medicine. Which is normally used for the immediate relief of symptoms related to allergic disease like allergic rhinitis and pruritus skin infection. On the other hand, it may also be used for the treatment of flu and related symptoms too. The most important thing to note is that Ebastine does not exhibit greater sedative or antimuscarinic effects than any other similar medicine available in the market today in the year 2023.
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What Is Ebastine And What Is It Used For?
The first thing we must know is that Ebastine is a second-generation H1-Anti Histamine medication with the lowest capacity to cause drowsiness in allergic patients. Moreover, the medication does not induce too much penetration to the blood-brain walls and incorporates the sufficient block of H1 Receptor in peripheral tissues generating very low incidence side effects. It was first discovered during studies in the year 1983 in the United States Of America. While it was first approved to use in medicines in 1990 in the USA. Now marketed under several brand names including Kestine Tablets, Ebast, Ebastel Flas, Tebast, etc
Composition Formula Ingredients
- 10 mg tablets contain Ebastine B.P. 10 mg.
- 20 mg tablets contain Ebastine B.P. 20 mg.
- Liquid Syrup 5 ml contains Ebastine B.P. 5 mg.
What Are its Uses & Indications?
Kestine syrup tablets represent the antihistamine activities and provide benefits and are commonly utilized for the therapy of allergy signs generated in the human body due to several types of different causes like
- Allergic rhinitis associated Hay Fever ( When patients face problems like a runny nose)
- Idiopathic chronic urticaria the nettle rashes.
- Allergic dermatitis.
- Sneezing Episodes
- Skin Rashes
- Flu & fever
What Is Its Dosage Recommendations?
The Dosage of this medicine totally depends on the severity of individual patients. So do not use any quantity of dose by yourself. Always take medicine only after your doctor or pharmacist recommend it for you.
Dose In Allergic Rhinitis:
Firstly, the recommended dose is Kestine 10MG once daily. However, in the event of severe symptoms, the Dosage may increase to Kestine 20MG once daily. Furthermore, this can take in two doses of 10mg or one dose of 20 mg.
Dose In Urticaria:
However, the adult dose is 10 MG orally daily. But, doctors or pharmacists may decide according to the patient’s condition.
Dosage For Allergic Dermatitis:
Furthermore, The adult dose is 10 mg of orally daily.
The dosage of oral Liquid is:
Adults And Children Over 12 Years Of Age:
The recommended doses are 10MG once daily.
Children Aged 6 to 11 years:
Once doses of 5 ml kestine liquid syrup suspension once a day.
Children Aged 2 to 5 Years:
The usual doses are 2.5 ml liquid syrup once a day.
Children Under 2 Years Of Age:
Most importantly, the safety of this medication has not been established for children under 2 years of age.
Uses In Special Groups
Older Patients:
Lastly, It is not necessary to adjust the dose.
Hepatic Insufficiency:
However, It is not necessary to adjust the dose in patients with mild or moderate liver impairment. Meanwhile, there is no experience with doses over 10 mg in patients with severe hepatic insufficiency. Therefore the dose of 10 mg per day should not be exceeded in these patients.
Contra-Indications Details
Most importantly the medicine is contraindicated to Hypersensitivity to the active ingredient of the medicine.
General Warnings And Precautions
- Most importantly, Caution should be taken when prescribing tablets in combination with azole antimycotic agents. On the other hand, type ketoconazole and itraconazole, or macrolide antibiotics type erythromycin.
- On the other hand, Caution should be taken when the medicine is prescribed with drugs belonging to antituberculosis type rifampicin.
- Ebastine Tab at recommended therapeutic doses does not affect the ability to drive or operate machines. However, insensitive subjects react unusually to the medicine. Therefore, It is advisable to know the individual reactions before patients drive or carry out complicated activities.
- Meanwhile, Patients with hereditary galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption should not take this medicinal product.
- This medicinal product may cause stomach upset and diarrhea because it contains polyethylene glycol.
- On the other hand, the Patient with rare hereditary problems of fructose intolerance should not take this medication.
May I Use It This Tab With Other Medicines I Am Already Using?
- Firstly, Pharmacokinetic interactions have been observed when these tablets are given with ketoconazole or itraconazole and erythromycin. Meanwhile, These Interactions resulted in increased plasma concentrations of these capsules.
- Secondly, Pharmacokinetics interactions have been observed when the medicine is given with rifampicin. However, These interactions could result in lower plasma concentrations and reduced antihistamine effects.
- Furthermore, No interactions have been reported between this medicine and theophylline, warfarin, cimetidine, diazepam, and alcohol.
Excipients Formula Ingredients Of Liquid Syrup
- Glycerin
- Lactic Acid
- Sorbitol
- Methyl Paraben Sodium
- Propyl Paraben Sodium
- Neohesperidine Dihydrochalcone
- Polyoxin 40 Hydrogenated Castor Oil
- Sodium Hydroxide
- Anethole
- Simethicone Emulsion
Excipients Formula Ingredients Of Tablet
- Microcrystalline Cellulose
- Lactose
- Croscarmellose sodium
- Pregelatinized Starch
- Magnesium stearate
- Hydroxypropyl Methylcellulose
- Polyethylene Glycol (6000)
- Titanium Dioxide (Just in 20MG Only)
Is Its Use In Pregnancy And Lactation Safe?
However, there are a limited amount of data on the use of the medicine in pregnancy. As a precautionary measure, it is preferable to avoid the use of this medication during pregnancy. Therefore, It is not known whether it is excreted in human milk. However, As a precautionary measure, it is preferable to avoid the use of this tablet during lactation.
Kestine (Ebastine) Side Effects
However, The commonly reported Side Effects are dry mouth and somnolence. Meanwhile, The other reported adverse effects are
- Hypersensitivity Reactions
- Nervousness
- Insomnia
- Headache
- Dizziness
- Hypoesthesia
- Dysgeusia
- Palpitations
- Tachycardia
- Abdominal pain
- Urticaria
- Rash
- Dermatitis
- Menstrual disorder
- Edema,
- Asthenia
Most importantly, if you face any of the described tablet side effects you may stop the medicine use and contact your doctor who will decide on the further use of the medication.
Overdosage Symptoms & Treatment Guide
Meanwhile, there is no specific antidote for this medicine. Gastric lavage, monitoring of vital functions including ECG, and symptomatic treatment are also carried out. Most importantly, you must remember to reach the nearby hospital or immediately contact your doctor in case of any medication overdose.
Meds Storage Instructions
Firstly, Keep out of the reach of children. Most importantly, Store below 30 C in a dry place. On the other hand, Protect from sunlight and heat. Lastly, you must read the product pack for its expiry date. And if the product is known as expired you must not use it.
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Kestine (Ebastine) 10MG, 20MG Tablets Capsules Price Details
- Price In Pakistan: 296 PKR
- Price In USA: $ 5 USD (Without Insurance Cost)
- Price In India: 185 INR
FAQ (Frequently Asked Questions) About Kestine Tab
- Q No.1: What Are Kestine Tablets?
Mainly it is a medication which normally indicated for the treatment of allergic conditions like seasonal allergies, hives, and rhinitis.
-
Q No.2: How Does This Medicine Work?
It works by blocking the action of a human body natural chemical named histamine which produce by the body during any type of allergic diseases. Therefore it provide immediate relief against these symptoms in a short time only.
Q. No. 3: Can Children Take This Medicine?
The most important thing is that this medicine is not recommended to use for by patients who aged below 12 years of age like children.
- Q.No.4: Can Kestine Tab Cause Any Type Of Drowsiness?
In only some rare cases it can cause drowsiness. So it’s important to avoid driving or operating any type of heavy machinery until you know how this medicine can affect one.