What Is Ospamox Tablets 500 MG 1000 MG 1GM Amoxicillin And What Are Its Uses & Side Effects?
Amoxicillin brand name is Ospamox Tablets available in 500mg and 100 mg form. Amoxicillin is an oral semisynthetic aminopenicillin similar to ampicillin. On the other hand amoxicillin is more stable to gastric acids and more bio available than other penicillin. In addition it has a broad spectrum antibiotic and has bacterial activity against many gram positive and gram negative bacteria. Which provide relief in ear, throat, skin and urinary tract infection symptoms. Meanwhile the medication first found during researched in Year 1958 in United States Of America. While it first approved to use in medicine in year 1972 and now selling under hundreds of brand names world wide available in tablets, capsules, syrup and injections form.
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Composition Formula Ingredients
- Each film -coated Tab contains 500 mg /1000 mg amoxicillin (as trihydrate).
- On the other hand, each Capsule contains 250 mg amoxicillin (as trihydrate).
- However, each 5 ml of reconstituted oral suspension contains 125 mg amoxicillin (as trihydrate)
Uses In Urdu Hindi
Ospamox Amoxicillin 500 MG 1 GM Tablets Uses & Indications
Amoxicillin (Ospamox) 250MG, 500MG, 1000MG tablets use for the treatment of the following infections in adults and children. Like
- Acute bacterial sinusitis
- In acute otitis media
- Acute streptococcal tonsillitis and pharyngitis
- Acute exacerbations of chronic bronchitis
- Community acquired pneumonia
- Acute cystitis
- Asymptomatic bacteriuria in pregnancy
- Acute pyelonephritis
- Typhoid and paratyphoid fever
- Dental abscess with spreading cellulitis
- Prosthetic joint infections
- Helicobacter pylori eradication
- Lyme disease
Moreover, it also indicated for the prophylaxis of endocarditis. So, consideration should be given to official guidance on the appropriate use of antibacterial agents.
Ospamox 500 MG 1 GM Contraindications
Hypersensitivity to the active substance, to any of the penicillin or to any of the excipients of Ospamox. On the other hand, history of a severe immediate hypersensitivity reactions Like. Anaphylaxis, to another beta-lactam agents Like. a cephalosporin, carbapenem or monobactam.
Ospamox Amoxicillin 1GM 500 MG Drug Interactions
Probenecid
Concomitant use of probenecid is not recommended. Probenecid decreases the renal tubular secretion of amoxicillin. Concomitant use of probenecid may result in increased and prolonged blood levels of this.
Allopurinol
Concurrent administration of allopurinol during treatment with it can increase the likelihood of allergic skin reactions.
Tetracyclines
Tetracyclines and other bacteriostatic medicinal products may interfere with the bactericidal effects of this medication.
Oral Anticoagulants
Oral anticoagulants and penicillin antibiotics have been widely used in practice without reported of interaction. However, in the literature ratio cases of increased international normalized ratio in patients maintained on acenocoumarin or warfarin and prescribed a course of this medication. If co-administration is necessary, the prothrombin time or international normalized ratio should be carefully monitored with the addition or withdrawal of amoxicillin. Moreover, adjustments in the necessary.
Methotrexate
However Penicillin may reduce the excretion of methotrexate causing a potential increase in toxicity. On the other hand always consult your doctor or pharmacist.
Use During Pregnancy And Lactation
Pregnancy
During Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity. Limited data on the use of amoxicillin during pregnancy in humans do not indicate on increased risk of congenital malformations. It may used in pregnancy when potential benefits out weigh the potential risks associated with treatment.
Breastfeeding
Moreover, this medicine is excreted into breast milk in small quantities with the possible risk of sensitization of the mucous membranes. And possible in the breast-fed infant. So that breast-feeding might have to be discontinued. However, it should only used during breast feeding after benefit/risk assessment by the physician in charge.
Fertility
There are no data on the effects of this medications on fertility in humans. reproductive studies in animals have shown no effects on fertility.
Effects On Ability To Drive And Use Machines
In addition, No studies on the effects on the ability to drive and use machines have been performed. However, undesirable effects may occur (e.g. allergic reactions, dizziness, convulsions), which may influence the ability to drive and use machines.
Tab Ospamox Amoxicillin 500 MG 1000 MG 1 GM Side Effects
Firstly, the most commonly reported adverse drug reactions(ADRs) are diarrhea, nausea and skin rash. However, the ADRs derived from clinical studies and post marketing surveillance with it, presented by MedDRA system organ class are listed below.
The following terminologies have used in order to classify the occurrence of side effects.
- Very Common = 1/10
- Common = 1/100 to <1 /10
- Uncommon = 1/ 1,000 to < 1/100
- Rare =1/10,000 to < 1/ 1,000
- Very rare =< 1/10,000
- Not known = Cannot be estimated from the available data.
Infections And Infestations
Very Rare : Mucocutaneous candidiasis
Blood And Lymphatic System Disorders
Very Rare : Reversible leucopenia (including severe neutropenia or agranulocytosis) reversible thrombocytopenia and bleeding time and prothrombin time.
Immune System Disorders
Very Rare : Severe allergic reactions, including angioneurotic oedema. Similarly, anaphylaxis, serum sickness and hypersensitivity vasculitis.
Not known : Jarisch Horkheimer reaction.
Nervous System Disorders
Very Rare : Hyperkinesia, dizziness and convulsions.
Gastrointestinal Disorders
Common : Diarrhea and nausea
Uncommon : Vomiting
Hepatobiliary Disorders
Very Rare : Hepatitis and cholestatic jaundice. On the other hand a moderate rise in AST and/or ALT
Skin And Subcutaneous Tissue Disorders
Common : Skin Rash
Uncommon : Urticaria and Pruritus
Very Rare : Skin reactions such as erythema multiformat, Stevens - Johnson syndrome, toxic epidermal necrolysis. On the other hand bullous and exfoliative dermatitis and acute generalized exanthemata’s pustulosis (AGEP).
Renal And Urinary Tract Disorders
Very Rare : Interstitial nephritis, crystal Luria.
Ospamox Overdosage Symptoms & Treatment
Symptoms And Signs Of Overdose
Gastrointestinal symptoms (such as nausea, vomiting and diarrhoea. And disturbance of the fluid electrolyte balances may be evident. On the other hand, Amoxicillin crystal Luria, in some cases leading to renal failure observed. Therefore, convulsions may occur in patients with impaired renal function or in those receiving high doses.
Treatment Of Ospamox Overdosage
Gastrointestinal symptoms may treated symptomatically, with attention to the water and electrolyte balance. On the other hand Amoxicillin can removed from the circulation by hemodialysis.
Ospamox Medicine Storage Instructions
Most importantly always keep all the medicine out of the reach of the children. Store the medicine within 25 C temperature. On the other hand protect it from direct sunlight and heat. Lastly, check the ospamax packing for its expiry date printed on each packing and if its expired do not use the medicine to avoid any of the serious life threats to your health.
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Ospamox (Amoxicillin) 250 MG, 500 MG, 1000 MG Tablets Price
- Price In Pakistan: 350 PKR
- Price In USA: 4 USD
- Price In India: 301 INR