What Is Sensival (Nortriptyline) Tablets 25 MG And What Are Its Uses Side Effects?
Sensival Tablets contains 25 MG Nortriptyline HCL in it which consider as one of the best tricyclic anti depressant medicine used for the treatment of depression and night time bedwetting in patients. Meanwhile Nortriptyline HCL is a tricyclic antidepressant of the dibenzo-cycloheptene type and is the active metabolite of amitriptyline. On the other hand, it is similar to protriptyline. Nortriptyline HCL used for the treatment of neurogenic pains. Some efficiency has reported with this medication in phobic disorders and some panic disorders.
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Sensival Tablets 25 MG Nortriptyline Uses
- Effective in all forms and degrees of depression.
- Relieves functional somatic type of depression.
- May be administered as single daily dose or in divided dosage.
- Wide margin of safety with low incidence of toxicity.
- Does not produce dependence pr addiction.
- May be used in the treatment of enuresis in children.
Uses In Urdu Hindi
Tab Composition Ingredients & Formula
Each Tab Contains Nortriptyline HCI BP equivalent to 25 mg.
This medication is the principle active metabolite of amitriptyline and has a longer plasma half life than that of amitriptyline. Meanwhile, It is subject to extensive first-pass metabolism in the liver to 10-hydroxynortriptyline, which is also active.
On the other hand, medication has specific therapeutic window between 50 and 150 mg per mL of plasma concentration, within which antidepressant responses occur. However, Above and blow this plasma rage, there is poor clinical response. Meanwhile, Plasma who do not respond to usual oral doses or in high risk patients, who because of the age or medical illness would best be treated with lowest oral dosage of the drug. (PAP) Am. J. Psychiat, 1985 , 142, 155.
Sensival Tablet 25 MG Uses & Indication
Sensival Tablets 25 MG used for the treatment of depression and nocturnal enuresis in patients when other organic pathology has been excluded. Meanwhile always consult your doctor of pharmacist who better understand the patient’s condition and may use this medicine in combination with some other products.
Sensival Tablet 25 MG Dosage And Administration
In depression dosage should be initiated at low level and increased gradually with the desired therapeutic response. Meanwhile, Initial adult dosage may be one tab of 25mg daily. However this may increased to 4 capsules 100mg daily divided dosage as necessary. On the other hand, increasing the dosage, the evening dosage should preferably be enhanced. Meanwhile, Since this medication has a prolonged half life, one daily dosage regimens are also suitable usually given at night.
Contraindications Details
Hypersensitivity to this medication or, use with monoamine oxidase inhibitors.
Precautions & Warnings Information
Meanwhile, it should used with caution in patients with, cardiovascular disease and should avoided in immediate recovery phase after myocardial infarction of heart block. However, Caution should observed in patients with history of epilepsy, untreated narrow angle glaucoma, urinary retention, prostatic hypertrophy or constipation. Meanwhile, its Use not recommended in mania.
However, Patients with suicidal tendencies should carefully supervised during treatment. On the other hand, Blood sugar concentration may altered in diabetic patients. Meanwhile, The effect of direct acting sympathomimetic drugs adrenaline and noradrenaline enhanced by tricyclic antidepressants. Meanwhile, The interaction liable to considerably more hazardous if these agent used intravenously. However, Drowsiness often experienced at the start of treatment with the medicine of Nortriptyline. And patients should not drive or operate machinery.
Sensival 25 MG Nortriptyline Tablets Side Effects
Like all the other medical products Sensival Tab also shown Side effects of medications and other tricyclic antidepressants include dry mouth as well as symptoms like
- Sour or metallic taste
- Constipation occasionally leading to paralytic ileus
- Urinary retention
- Blurred vision
- Palpitation
- Tachycardia and impotence
Other adverse side effects may include drowsiness (but some times nervousness and insomnia may occur but only in some patients
- Headache
- Peripheral neuropathy
- Tremor
- Orthostatic hypotension
- Occasionally hypertension
- Dizziness
- Sweating
- Weakness
- Fatigue
- Ataxia
- Epileptiform seizures
- Occasional Extrapyramidal symptoms including speech difficulties
- Tinnitus
- Stomatitis and gastric irritation with nausea and vomiting
- Confusion or delirium may occur
- Particularly in the elderly
- Anorexia with weight loss or weight gain
- Sometimes with inappropriate appetite may occur
- Allergic skin reactions and photosensitization have reported and rarely
- Cholestatic jaundice and blood disorders, Including eosinophilia
- Bone marrow depression
- Thrombocytopenia
- Leucopenia and agranulocytosis
However, The tricyclic anti-depressants have an adverse effects on myocardium and can cause conduction defects and cardiac arrhythmias, and an increased risk of sudden death has been suspected in cardiac patients taking these drugs. Endocrine effects associated with this medication and other tricyclic antidepressants include changes in libido, interference with changes in blood sugar concentrations may occur and very rarely inappropriate secretion of antidiuretics hormone.
Tab Overdosage Symptoms & Treatment Information
In case of any overdosage symptoms are excitement and restlessness marked with dry mouth
- Dilated pupils
- Tachycardia
- Urinary retention and intestinal stasis
- Severe Symptoms Include unconsciousness
- Convulsion and myoclonus hyperflexia
- Hypertension
Respiratory and cardiac depression with life threatening arrhythmias may occur some days after apparent recovery.
Sensival 25 MG Tablets Storage Instructions Guide
Most importantly keep all your medicines out of the reach of your children present at home. On the other hand, store the tab below 30C temperature. In addition also protect it from direct sunlight and heat. Lastly, always check the nortriptyline capsules packing for its expiry date and if the medicine expired do not use it to avoid any type of un usual side effects.
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Sensival Nortriptyline Tablet 25 MG Price Details
- Price In Pakistan: 599 PKR
- Price In India: 510 INR
- Price In USA: 4 USD