Maxolon Tablets Syrup Injection Metoclopramide 10 MG Uses Dosage Side Effects Price

What Are Maxolon Tablets, Syrup, Injection And Its Uses Dosage Side Effects?

Maxolon Tablets, Injection, Syrup is the formulation of a useful drug named Metoclopramide HCL. It generally indicated and used for the treatment of symptoms like vomiting and nausea. Moreover it also helps in the prevention of delayed stomach emptying and gastroesophageal reflux in patients in severe cases. Most importantly this medications consider as best antiemetic with dopamine antagonist action in brain and peripheral effect on gastro intestinal tract. Where it stimulates motility to improve gastric emptying and intestinal transit. Meanwhile, Metoclopramide HCL used to treat nausea and vomiting of most causes and as an adjunct to X-ray examination of the gut.  It used both orally and parentally.

What Is Metoclopramide HCL And What It Used For?

Metoclopramide HCL is generally D2 receptor antagonist medications. It generally used for the treatment of esophageal and stomach problems in humans both adults and children. Meanwhile it sold under different brand names world wide including Maxolon, Primperan, and Relgan. The mechanism of action of Metoclopramide HCL due to its antagonist activity prevent the nausea and vomiting effectively. Most importantly, the medication first found during research in Year 1964 and first approved to use in medicines in year 1975 in USA.

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 Tablets, Syrup, Injection Pharmacology Information

The action of Maxolon Tablets, Syrup, Injection closely associated with parasympathetic nervous control of the upper gastrointestinal tracts. Where the medicine has the effects to encourage normal peristaltic action. This provides  approach to the treatment of those conditions where disturbed gastrointestinal motility a common underlying factor.

Uses In Hindi Urdu

Maxolon Tablets Syrup Injection Uses & Indications

Maxolon Uses In Adults (20 Years And Over)

Digestive Symptoms Includes:

• Dyspepsia
• Heatburn
• Flatulence
• Sickness
• Regurgitation Of Bile
• Pain

Its Use In Digestive Disorder Conditions Like:

• Peptic Ulcer
• Duodenitis
• Reflux Oesophagitis
• Hiatus Hernia
• Gastritis
• Cholelithlasis And Post Cholecystectomy Dyspepsia
• Post Operative Gastric Hypotonia
• Post Vagotomy Syndrome

It generally promotes normal gastric emptying and restores motility in vagotomised patients and when post operative symptoms suggest gastro duodenal dysfunction.

Nausesa And Vomiting Associated With:

• Gastro Intestinal Disorders
• Intolerance to essential drugs including digitalis antibacterial and cytotoxic drugs Congestive heart failure
• Deep X-ray or cobalt therapy
• Post anaesthetic vomiting

Diagnostic Procedures

Radiology:     it speeds up the passage of barium meal by decreasing gastric emptying time, co-ordinating Duodenal Intubation     Peristalsis and dilating the duodenal bulb, Mazolon also facilitates duodenal intubation procedures. Migraine:          medicine relieves symptoms of nausea and vomiting and overcomes gastric stasis associated with migraine. This improvement in gastric emptying assists the absorption of concurrently administered oral anti migraine therapy like. paracetamol which may otherwise be impaired in such patients. The Maxolon Use in patients under 20 years should be restricted to the following:

• Severe intractable vomiting of known cause.
• Also vomiting which associated with radiotherapy and intolerance to cytotoxic drug.
• As an aid to gastro intestinal intubation and diagnostic radiology.
• As part of the premedication before surgical procedures.

Maxolon Tablets Syrup Injection Dosage And Administration

The Maxolon Tablets, Syrup, Injection Dosage recommendation given below should be strictly adhered to if side effects of the dystonictype are to be avoid. It should be noted that total daily Dosage especially for children and young adults should not normally exceed 0.5 mg/kg body weight.

Oral Dosage

Adults 15 years and over:   with weight of 60 kg or more Maxolon 10 mg dose used three times daily. Adults 15 years and over:   less than 60 kg body weight Maxolon 5 mg three times daily. Injection, Tablets, Syrup should only be used after careful examination to avoid masking an underlying disorder e.g. Cerebal irritation in the treatment of young adults. On the other hand, children attention should given primarily to body weight and treatment should commence at the lower dosage where stated.

Maxolon Dose For Children

• 9 – 14 years           30 kg and over         5 mg three times daily
• 5 – 9 years              20 – 29 kg                    2.5 mg three times daily
• 3 – 5 years              15 – 19 kg                    2 mg two to three times daily
• 1 – 3 years              10 – 14 kg                   1 mg two to three times daily
• under 1 year         up to 10 kg                1 mg twice daily

Furthermore, A liquid presentation should used in the younger age groups as the facilitates accurate dosage and administration.

I.M. or I.V Injection Dosage

Maxolon Injection may be administered at the dosage stated above either intramuscularly or by slow intravenous injection (1 – 2 minutes)

Radiological And Indicational Indication

A single dose of Maxolon Medicine may be given 5 – 10 minutes before examinations. Subject to body weight consideration the following dosage recommended. Adults                       20 Years And Over               10 – 20 mg Young Adults        15 – 19 Years                             10 mg Children                   9 – 14 Years                                5 mg 5 – 9 Years                                   2.5 mg 3 – 5 Years                                   2 mg Under 3 Years                          1 mg

Indications For High Dose Intravenous Therapy

Treatment of nausea and vomiting associated with intolerance to cytotoxic drugs. Dosage And Administration:     2 mg/kg body weight by Maxolon I.V. infusion. It recommended that each dose should added to at least 50 mg of an appropriate diluent and infused over at least 15 minutes. the initial dose should given prior to commencement of cytotoxic chemotherapy. However, Dosage may repeated 2 hourly up to a maximum of 10 mg/kg body weight in any 24 hour period.

The Cytotoxic Agent Should  Administered As a Separate Infusion

Stability In Intravenous Solution Intravenous solution should prepared as near as possible to the time of use. The medicine shown to stable in the solutions listed below for at least 24 hours at the temperature of 25 C.

• Sodium Chloride Intravenous Infusion BP 0.9% w/v
• Glucose Intravenous Infusion BP 5% w/v
• Sodium Chloride and Glucose Intravenous Infusion BP sod, chlor 0.18% w/v, glucose 4% w/v
• Compound Sodium Lactate Intravenous Infusion BP, and ringer lactate solution or  Hartmann’s solution

Drug Special Precautions If vomiting persists the patient should re-assessed to exclude the possibility of an underlying disorder for example cerebral irritation. After the operations Like pyloroplasty or gut anastomosis Maxolon Drug therapy  should  withheld for 3 or 4 days as vigorous muscular contractions may not help healing Since extra-pyramidal symptoms may occur both medicine and neuroleptics such as phenothaiazines, particular care should exercised in the event of these drugs being prescribed concurrently Consequently, The action of this medicine on the gastro-intestinal tract antagonised by anticholinergics. The absorption on any concurrently administered oral medication may modified by the effect of tablets on gastric motility.

Maxolon Uses In Pregnancy

About the use of Maxolon In Pregnancy the Animal test in several mammalian species and clinical experience have not indicated a teratogenic effect. nevertheless. It should be used when they are compelling reasons and and it not advised during the first trimestar.

Use In Abnormal Renal Or Liver Function

Meanwhile, In patients with clinically significant degrees of renal or hepatic, impairment oral, I.V or I.M therapy should be initiated at half the usual doze. subsequent usage will depend on the individual clinical response.

Use For Elderly patients

Furthermore, to avoid adverse reactions adhere strictly to dosage recommendations where prolonged therapy considered necessary should regularly reviewed.

Maxolon Syrup Tablet Capsules Injection Side Effects

Many kind of extra-pyramidal Maxolon Side Effects usually have been reported. The incidence of these reactions, particularly in children and young adults increased if daily dosages higher then 0.5 mg/kg body weight administered. Dystonic reactions include:

• Spasm of the facial muscles
• Trismus
• Rhythmic profusion of the tongue
• Bulbar type of speech
• Spasm of extra-ocular muscles
• Oculogyric crises
• Unnatural positioning of the head and shoulders
• Opisthodomos

Furthermore, There may be a generalized increase in the muscle tone. However, The majority of its  Side Effects occur within thirty six hours of starting treatment and the effects usually disappear within twenty four hours of withdrawal of the drug. So, treatment of a dystonic reaction required an anticholinergic anti-Parkinson drugs of benzodiazepine may used. Tardive dyskinesia has reported during prolonged treatment in a small number of mainly elderly patients. So, Patients on prolonged treatment should regularly reviewed. Furthermore, Metoclopramide may induce an acute hypertensive reports in patients with pheochromocytoma. Raised serum prolactin levels have   observed during Metoclopramide therapy. Meanwhile, this effect is similar to that noted with many other compounds. Therefore, when given at high dose in connection with cancer chemotherapy. The drug has well tolerated with few side effects, the most common being mild sedations. In conclusion, you must contact your doctor or pharmacist or got to nearly hospital if any side effects shown.

Tab Syp Cap Overdose Symptoms & Treatment

The Overdose should be treated by gastric lavage with appropriate supportive measures. Most importantly, immediately contact your doctor or go to hospital.

Drug Storage Instructions

Firstly, Store this Drug below 25 C and protect the medicine from heat and sunlight. However, If ampoules inadvertently exposed to light, any that show a yellow discoloration must discarded. On the other hand, most importantly, protect your children by keeping your medical products out of the reach of your children.

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Maxolon Metoclopramide Syrup, Injection, Tablets Price Details

Price In Pakistan:

• Tab/Cap Price: 185 PKR
• Syp Price: 95 PKR
• Inj Price: 310 PKR

The Price In India:

• Tab / Cap Price: 175 INR
• Syp Price: 88 INR
• Inj Price: 285 INR

Price In USA:

• Tab / Cap Price: 3 USD
• Syp Price: 2 USD
• Inj Price: 4 USD

 

Disclaimer

All the details of the medicine provided on this website Pharmacy Online Here are only for informational purposes and there is no intent to substitute for professional medical advice, diagnostic, and treatment purposes. Therefore, always get medical advice from any qualified healthcare provider doctor, or pharmacist for any questions about your medical conditions, symptoms, or disorder. So do not disregard the medical advice of your professional healthcare provider or delay it simply because of the information your read here on this website.  Note:– Always Use Any Type Of Medicines Only Under The Supervision Of A Professional Healthcare Provider, Doctor, Or Pharmacist.