A Comprehensive Guide Of Qluz Tablets Uses Side Effects Price

Qluz Tablets Injections Uses Dosage Side Effects Details

The medicine brand name is Qluz Tablets. On the other hand these Tablets And Injection chemical name is 4 hydroxyl 2 methyl 2  methyl  n- 2 pyridinyl  2h 1.2 bezothiazine -3 carboxamide 1  , 1 diaoxide. However The molecular weight is 331. 35 lts molecular formula is C15 H1 N3 O4 S medicine occurs as a white crystalline solid. sparingly soluble in water , dilute acid and organic solvents. On the other hand It is slightly soluble in alcohol and in aqueous solutions. So, medicine is a nonsteroidal anti-inflammatory drug which possesses analgesic and antipyretic properties. In Addition, it is structually unrelated to other NSAIDs. In Short, All the Drug Information of the product is as under.

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Qluz Tablets Indications

(Qluz) Tablets Injection is a Nonsteroidal anti-inflammatory drug . In Addition it indicated for a variety of conditions requiring anti-inflammatory and analgesic activity.  For Example

• Rheumatoid Arthritis
• Juvenile Rheumatoid Arthritis
• Osteoarthritis
• Arthrosis
• Degenerative joint the disease
• Ankylosing Spondylitis
• Acute Musuloskeletal Disorders
• Acute Gout
• Pain after operative intervention and following acute trauma
• For the treatment of primary dysmenorrhea in patients 12 years of age or older
• For the treatment of the symptoms of fever and pain which associated with acute upper respiratory tract inflammation

Tablets/Injections Dosage Administration

I.M. Injection:

Above all, the daily dose is 20 mg/ml injection given as one  single daily dose. The I.M intramuscular injections  identical to the dosage of oral medicine. On the other hand, For continuation of treatment oral dose forms should used. On the other hand the medicine should administration by deep intramuscular injections into the upper, outer quadrant of the buttock. Therefore, While the intramuscular injection should not administered intravenously.

Tablets

Rheumatoid arthritis , Osteoarthritis (Arthrosis, Degenerative Joint Disease ) Ankylosing Spondylitis Firstly, The recommended starting dosage  20 mg given as a single daily dose. And secondly, the majority of patients maintained on 20 mg daily. A relatively small group of patients may be maintained on 10 mg daily. On the other hand Some patients may require up to 30 mg daily given in single or divided doses. Meanwhile, Long term administration of Doses 30 mg or higher an carries an increased risk of gastrointestinal side effects.

Acute Gout

Therapy should be initiated by a single dose of 40 mg. And it must follow  for the next 4 to 6 days with  Tablets/Injection 40 mg daily. However, Given in single or divided doses. To sum up, This medicine  not indicated for the long term management of gout.

Acute Muculoskeletal Disorders

Therapy should be initiated with 40 mg daily for the first two days given in single or divided. However, For the remainder of the 7 to 14 day treatment period the dose should be reduced 20 mg daily .

Postoperative And Posttraumatic Pain

The recommended staring  Dosage is 20 mg given as a single daily dose. However, in some cases where a more rapid onset of action have to achieve. Most importantly the Therapy should initiated with 40 mg daily for the first two days. On the other hand it given in single or divided doses. For the remainder of the treatment period the dose should reduced to 20 mg daily.

Dysmenorehea

The treatment of primary dysmenorrhea is initiated at the earliest onset of symptoms with a recommended starting dose of 40 mg. It given as a single daily dose for the first two days. So, Treatment may continued therapy with a single daily dose of 20 mg for the next one to three days as necessary.

Upper Respiratory

The usual adult dosage is 10 or 20 mg orally once daily. On the other hand In cases where a more rapid onset of action is is desired. Therapy should initiated with  40 mg once daily for the first two days. In addition, followed by 10 or 20 mg daily for there to five days.

Qluz  Tablets Contraindications

The Injections/Tablets should not used in those patients who have previously shown a hypersensitivity to the drug. The potential exists for cross sensitivity to Aspirin and other Nonsteroidal anti-inflammatory drug. Therefore, it should not given to patients in whom aspirin and other Nonsteroidal anti-inflammatory drugs induce the symptoms. Like

• Asthma
• Nasal Polyps
• Angioedema
• Urticaria

Qluz  Warnings

Infrequent incidences of peptic ulceration, perforation and gastrointestinal bleeding, in rare cases fatal, have reported with this medicine. So Drugs administration should closely supervised in patients with a history of upper gastrointestinal disease. Furthermore, In some rare cases NSAIDs may cause symptoms like interstitial nephritis, glomerulitis, papillary necrosis and the nephrotic syndrome. NSAIDs inhibit the synthesis of renal prostaglandin. Which plays a supportive role in the maintenance of renal perfusion in patients whose renal blood flow and blood volume are decreased. In these patients administration of an NSAIDs may precipitate over renal decompensation. Which is typically followed by recovery to pre-treatment conditions upon discontinuation of NSAIDs therapy. However the Patients at greatest risk of such a reaction are those with congestive heart failure, liver cirrhosis, nephrotic syndrome and overt renal disease. Such patients should carefully monitored while receiving Non-steroidal anti-inflammatory drugs therapy. Because of reports of adverse eye findings with Non-steroidal anti-inflammatory drugs. It is recommended that patients who develop visual complaints during treatment with this medicine have an ophthalmic evaluation. When used for the relief of pain and inflammation in upper respiratory tract inflammation. It should remembered that NSAIDs are only a symptoms therapy. So, when given to patients with such conditions , appropriate concomitant antibacterial therapy considered .

Qluz Drug Interactions

Highly Protein Bound Drugs: it is highly protein bound and therefore might expected to displace other protein bound drugs. Aspirin: When the medicine administration with Aspirin its protein binding reduced, although the clearance of free medicine not altered. Plasma levels of this medicine depressed to approximately 80% of their normal values. Therefore, when it administered (20mg/day) in conjunction with Aspirin (3900 mg/day). Methotrexate: This may indicate that they could enhance the toxicity of methotrexate. Most importantly, caution should used when NSAIDs administered concomitantly with Methotrexate . ACE Inhibitors; Reports suggest that NSAID may diminish the anti-hypertensive effects of ACE inhibitors. Therefore, This interaction should given consideration in patients taking NSAID concomitantly with ACE inhibitors. Lithium: NSAID have produced an elevation of plasma Lithium levels and a reduction in renal Lithium clearance. However, when NSAID and Lithium administered concurrently, subjects should observed carefully for signs of Lithium toxicity. Warfarin: The effects of Warfarin and NSAID on GI bleeding are synergistic. Like, that users of both drugs together have a risk of serious GL bleeding higher than users of either drugs alone.

Qluz Tablets During Pregnancy And Lactation

Pregnancy There are no data yet available about Qulz Tablet Use in pregnant women. So, it not recommended for use in pregnant women since safety has not established in humans. On the other hand the medicine should used in pregnancy only if the potential benefit justifies the potential risk to the fetus. Laction Mainly it excreted into human milk. The presence in breast milk has determined during initial and long term conditions (52 days). Therefore, it appeared in breast milk at about 1 to 3 of the maternal concentration. On the other hand the medicine not recommended for use in nursing mothers.

Qluz Side Effects

Drug Side Effects included: Like

• Swelling
• Anorezia
• Abdominal Pain
• Constipation
• Diarrhea
• Indigestion
• Heart burn
• Upset Stomach
• Stomach Pain
• Elevated Liver Enzymes
• Bloating
• Gas
• Gross Bleeding Perforation
• Heartburn
• Nausea
• Ulcers (gastric/duodenal )
• Dizziness
• Headache
• Nervousness
• Skin Itching
• Rash
• Blurred Vision
• Ringing in your ears
• Vomiting

Qluz Tablets  Adverse Drug Recations

The following adverse reaction have identified during post approval use of (Qluz). Because these reactions reported voluntarily from a population of uncertain size. It not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. If you notice any of the side effects you must immediately contact your doctor or pharmacist. Body as whole:

•  Fever
• Infection
• Sepsis
• Anaphylactic Reactions
• Apetite Changes
• Death
• Flu like Syndrome
• Pain (colic)
• Serum Sickness

Cardio Vascular System: Congestive heart failure, hypertension, tachycardia, syncope, arrhythmia, exacerbation of angina, hypotension. Digestive System: Dyspepsia, elevated liver enzymes, heart burn, ulcers, dry mouth, esophagitis, hepatic, jaundice, rectal bleeding, liver failure, pancreatitis. Hemic And Lymphatic System: Anemia, increased bleeding time, ecchymosis, eosinophilia, leukopenia, purpura and thrombocytopenia.  Agranulocytosis, hemolytic anemia, aplastic anermia, lymphadenophathy, pancytopenia. Nervous System: Anxiety, confusion, depression, dream abnormalities, insomina, malaise, nervousness and paresthesia. Also somnolence, tremors, akathisia, convulsions, coma, hallucinations, meningilis, mood alterations. Respiratory System: Asthma, dyspnea, respiratory depression, pneumonia. Skin And Appendages: Alopecia, bruising, erythema, photosensitivity, sweat, angioedema, toxic epidermal necrosis. And erythema multiforme, exicliative dermatitis, stevens johnson syndrone, urticaria. Special Senses: Conjunctivitis, hearing impairment, swollen eyes. Urogenital System: Abnormal renal function, cystitis, clysuria, hyperkalemia, interstitial nephritis, nephrotic syndrome, oliguria/polyuria, renal failure.

Overdosage Symptoms & Treatment

Symptoms following acute NSAID overdosage have typically limited to lethargy, drowsiness, nausea, vomiting and epigastric pain. However these are generally reversible with supportive care. Gastrointestinal bleeding has occurred. Hypertension, acute renal failure, respiratory depression and coma have occurred but rare. So, There are no specific antidotes. Consider emesis and activated charcoal (60-100 grams in adults 1-2 grams per kg of body weight in pediatric patients). However osmotic cathartic in symptoms patients seen within four hours of ingestion. Or in patients with a large over dosage (5 to 10 times the recommended ). Therefore the long plasma half life of the medicine should considered when treating an overedose with this medication. On the other hand Forced diuresis, alkalinization of urine, hemodialysis or hemoperfusion may not be useful due to high protein binding .

Drug Storage Guide

Most importantly, Store the drug in a cool and dry place and keep the drug below 25 C temperature. Protect the medicine from sun light and heat. Most importantly, always keep all your medical products out of the reach of your small kids.

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