Nootropil Tablets Injection (Piracetam) Uses, Dosage, Side Effects Benefits Formula Ingredients Price Details

Nootropil Tablets Injection Uses Dosage Details

Nootropil Tablets Injection contains Piracetam which is an anticonvulsants. Piracetam Uses as an adjunct to other drug in cortical myoclonus (spontaneous jerky movement in epilepsy).

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Nootropil Tablets Injection Uses & Indications

Adults

Nootropil Uses for Symptomatic treatment of the psycho organic syndrome whose features improved by treatment are

• Memory loss,
• Attention disorders and lack of drive,
• Treatment of cortical myoclonus, alone or in combination,
• Treatment of vertigo

And associated disorders of balance, with the exception of dizziness of vasomotor or psychic origin. Prophylxis and remission of sickle cell vaso occlusive crises.

Children

Treatment of dyslexia, in combination with appropriate measures such as speech therapy, prophylaxis and remission of sickle cell vaso occlusive crises.

Nootropil (Piracetam) Tablets Dosage And Administration

This medication must used as directed by physician.

Oral Formulation

Piracetam Drug may be taken with or without food. The film coated capsules should be dissolved in liquid. It recommended to take the daily dose in two to four sub doses.

Parenteral Formulation

When parenteral administration needed e.g. swallowing difficulties, unconsciousness. The medication can administered intravenously at the same recommended daily dose. The Nootropil solution for injection will administered intravenously over several minutes. And Nootropil solution for infusion will administered continuously at the recommended daily dose over a 24 hour period.

Dose For Adults

Symptomatic Treatment Of Psycho Organic Syndromes The recommended daily Nootropil dosage ranges from 2.4 g to 4.8 g in two or three sub doses. Treatment Of Myoclonus Of Cortical Origin The daily dosage should begin at 7.2 g increasing by 4.8 g every three or four days up to a maximum of 24 g in two or three divided doses. Treatment Of Vertigo The recommended daily dose ranges from 2.4 g to 4.8 g in two or three divided doses. Prophylaxis And Remission Of Sickle Cell Vasoocclusive Crises Most importantly, the recommended daily dose for prophylaxis  160 mg/kg orally in four divided doses. Therefore, the recommended daily dose for remission 300 mg/kg intravenously in four divided doses. Meanwhile, for sickle cell anaemia the prophylactic  dosage must be permanent. Therefore, the dose lower than 160 mg/kg/day or irregular intake may result in relapse of crises.

Dosage For Children

Dyslexia Firstly, The recommended dosage for school age children (from 8 years old) and adolescent is 3.2 g per day. That means Nootropil 8 ml of 20% solution twice per day or 2 capsules of 800 mg in the morning and in the evening usually during the whole period of the school year. Prophylaxis and remission of sickle cell vaso-occlusive crises Meanwhile, For children from 3 years old onwards the prophylactic dosage 160 mg/kg/day day divided into 4 divided doses. However, In case of remission a dose of 300mg/kg/day administered intravenously divided into 4 divided doses. So, the prophylactic administration in sickle cell anaemiamust be permanent. However, A dose lower than 160mg/kg/day or an irregular intake may cause a relapse of the illness. Furthermore, it  administered to children with sickle cell anaemia indication in recommended daily doses (mg/kg/day). Consequently, it generally has administered only to a limited number of children in the age range of 1 to 3 years.

Dosage For Elderly

Most importantly, the adjustment of the dosage is recommended in elderly patients with compromised renal function. On the other hand, for long term treatment in the elderly regular evaluation of the creatinine clearance required to allow dosage adaptation if needed.

Renal Impairment

Firstly, its contraindicated in severe renal impairment (renal creatinine clearance of less than 20 ml per minute). The daily dose must be individualized according to renal function. Meanwhile, refer to the following table and adjust the dose as indicated. To use this ml/min  needed. The Clcr in ml/min may  estimated from serum creatinine (mg/dl) determination using the following formula:

Hepatic Impairment Dose

Meanwhile, No dose adjustment is needed in patients with solely hepatic impairment. However, In patients with hepatic impairment and renal impairment, dosage adjustment is recommended.

Contraindications Details

Most importantly, its contraindicated in Hypersensitivity to piracetam, other pyrrolidone derivatives or any of the excipients, end stage renal disease (renal creatinine clearance of less than 20 ml per minute). Cerebral haemmorrhage.

Warning And Precautions Help

Effects on platelet aggregation

Firstly, Due to the Piracetam Side Effects on platelet aggregation, caution is recommended in patients with

• Severe haemorrhage,
• At risk of bleeding such as gastrointestinal ulcer
• Patients with underlying disorders of haemostasis
• With a  history of haemorrhagic CVA
• Patients undergoing major surgery including dental surgery
• Patients using anticoagulants or platelet antiagregant drugs including low dose of aspirin.

Renal Insufficiency

Meanwhile, it eliminated via the kidneys and care should thus betaken in cases of renal insufficiency.

Elderly

Consequently, for long term treatment in the elderly, regularly evaluation of the creatinine clearance is required to allow the dose of adaptation if needed.

Discontinuation

Furthermore, abrupt discontinuation of treatment with this medication should avoided as this may induce myoclonic or generalised seizures in some myoclonic patients.

Sickle Cell Vaso-Occlusive Crises

On the other hand, for sickle cell indication a dose lower than 160 mg/kg/day or irregular intake may result in relapse of crises.

Huntington’s disease

Meanwhile, when administering high dose to patients with Hunntington’s Disease a slight deterioration of spontaneous movements was observed.

Drug Interactions Guide

Acenocoumarol, antiepileptic drugs and alcohol. The medicine interaction may result in changes of Piracetam pharmacokinetics expected to be low because approximately 90% of the dose of this drug is excreted in the urine as unchanged drug. Confusion, irritability and sleep disorder have  reported during concomitant treatment with thyroid extract (T3+T4) Use In During Pregnancy And Lactation However, Use of the drug during pregnancy and lactation Not recommended. But your doctor or pharmacist will decide according to the condition of an individual patient.

Nootropil (Piracetam) Side Effects

Common:               Nervousness, Hyperkinesias, Weight increased Not Known:          Haemorrhagic disorder, anaphylactoid reaction, hypersensitivity, agitation, anaxiety, confusion, hallucination, ataxia, balance disorder, epilepsy, headache, insomnia, vertigo, abdominal pain, diarrhoea, nausea, vomiting, angioedema, dermatitis, pruritus, urticaria Uncommon:          Depression, somnolence, asthenia Rare:                          Thrombophlebitis (only parenteral formulation, hypotension (only parenteral formulations, pyrexia (only parenteral formulations), pain at the place of injection (only parenteral formulations).

Overdosage Symptoms & Treatment

However, No additional adverse side effects specifically related to overdose have been reported with Piracetam Drug. But The maximum reported overdose with its studied oral intake of 75 g. wherein bloody diarrhoea with abdominal pain was most probably related to the extreme high dose of sorbitol contained in the used formulation

Medicine Storage Guide

Most importantly, store the tablets below 30 c temperature and protect from sunlight and heat and moisture. While on the other hand, store syrup store below 30 C temperature, protect from sunlight, freezing and excessive heat. Furthermore, always remember to keep all your medical products syrups tablets etc out of the reach of your small children at home.

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Nootropil (Piracetam) Tablets, Injection, Syrup Price (Rs. 324 PKR)

 

Disclaimer

All the details of the medicine provided on this website Pharmacy Online Here are only for informational purposes and there is no intent to substitute for professional medical advice, diagnostic, and treatment purposes. Therefore, always get medical advice from any qualified healthcare provider doctor, or pharmacist for any questions about your medical conditions, symptoms, or disorder. So do not disregard the medical advice of your professional healthcare provider or delay it simply because of the information your read here on this website.  Note:– Always Use Any Type Of Medicines Only Under The Supervision Of A Professional Healthcare Provider, Doctor, Or Pharmacist.